proglumide
SMILES | CCCN(C(=O)C(NC(=O)c1ccccc1)CCC(=O)O)CCC |
InChIKey | DGMKFQYCZXERLX-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 2 |
Rotatable bonds | 10 |
Molecular weight (Da) | 334.2 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | Yes |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
CCK1 | CCKAR | Rat | Cholecystokinin | A | pIC50 | 2.2 | 2.2 | 2.2 | Guide to Pharmacology |
H2 | HRH2 | Rat | Histamine | A | pIC50 | 2.6 | 2.6 | 2.6 | ChEMBL |
H2 | HRH2 | Rat | Histamine | A | pIC50 | 8.59 | 8.59 | 8.59 | Drug Central |