CHEMBL289614


SMILES CCCCOC(=O)NS(=O)(=O)c1ccc(CC(C)C)cc1-c1ccc(Cn2c(CC)nc3c(C)cc(C)nc32)cc1
InChIKey GABMQILPAPONQS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 11
Molecular weight (Da) 576.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT1 AGTR1 Pig Angiotensin A pKi 9.15 9.15 9.15 ChEMBL
AT1 AGTRA Rat Angiotensin A pKi 8.68 8.68 8.68 ChEMBL
AT2 AGTR2 Human Angiotensin A pKi 8.68 8.68 8.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT2 AGTR2 Human Angiotensin A pIC50 9.15 9.15 9.15 ChEMBL
AT1 AGTR1 Human Angiotensin A pIC50 8.68 8.68 8.68 ChEMBL