Ligand source activities (1 row/activity)
Ligands (move mouse cursor over ligand name to see structure) | Receptor | Assay information | Chemical information | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name |
GPCRdb ID |
#Vendors |
Reference ligand |
Fold selectivity |
# Tested GPCRs |
Species |
p-value (-log) |
Activity Type |
Activity Relation |
Activity Value |
AssayType |
Assay Description |
Source |
Mol weight |
Rot Bonds |
H don |
H acc |
LogP |
Smiles |
DOI |
5311263 | 10929 | 22 | None | -36 | 7 | Mouse | 6.6 | pEC50 | = | 6.6 | Functional | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1021/jm5007116 | ||
CHEMBL117021 | 10929 | 22 | None | -36 | 7 | Mouse | 6.6 | pEC50 | = | 6.6 | Functional | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1021/jm5007116 | ||
2906 | 9134 | 18 | None | -72 | 12 | Human | 6.2 | pEC50 | = | 6.2 | Functional | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 10.1021/acs.jmedchem.6b01270 | ||
5395 | 9134 | 18 | None | -72 | 12 | Human | 6.2 | pEC50 | = | 6.2 | Functional | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 10.1021/acs.jmedchem.6b01270 | ||
5497152 | 9134 | 18 | None | -72 | 12 | Human | 6.2 | pEC50 | = | 6.2 | Functional | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 10.1021/acs.jmedchem.6b01270 | ||
CHEMBL1222042 | 9134 | 18 | None | -72 | 12 | Human | 6.2 | pEC50 | = | 6.2 | Functional | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 10.1021/acs.jmedchem.6b01270 | ||
122191544 | 130481 | 0 | None | 4 | 4 | Human | 6.6 | pIC50 | = | 6.6 | Functional | ChEMBL | 484 | 18 | 3 | 4 | 5.4 | CCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)CC(Br)P(=O)(O)O | 10.1039/C4MD00333K | ||
CHEMBL3621964 | 130481 | 0 | None | 4 | 4 | Human | 6.6 | pIC50 | = | 6.6 | Functional | ChEMBL | 484 | 18 | 3 | 4 | 5.4 | CCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)CC(Br)P(=O)(O)O | 10.1039/C4MD00333K | ||
16725999 | 7518 | 1 | None | - | 2 | Human | 6.8 | pKi | = | 6.8 | Functional | ChEMBL | 486 | 19 | 3 | 4 | 5.7 | CCCCCCCCCCCCCCCC(=O)OC[C@H](CC(P(=O)(O)O)Br)O | 10.1039/C4MD00255E | ||
6985 | 7518 | 1 | None | - | 2 | Human | 6.8 | pKi | = | 6.8 | Functional | ChEMBL | 486 | 19 | 3 | 4 | 5.7 | CCCCCCCCCCCCCCCC(=O)OC[C@H](CC(P(=O)(O)O)Br)O | 10.1039/C4MD00255E | ||
CHEMBL3621357 | 7518 | 1 | None | - | 2 | Human | 6.8 | pKi | = | 6.8 | Functional | ChEMBL | 486 | 19 | 3 | 4 | 5.7 | CCCCCCCCCCCCCCCC(=O)OC[C@H](CC(P(=O)(O)O)Br)O | 10.1039/C4MD00255E | ||
87470750 | 130595 | 0 | None | - | 0 | Human | 6.8 | pKi | = | 6.8 | Functional | ChEMBL | 512 | 20 | 3 | 4 | 6.2 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)CC(Br)P(=O)(O)O | 10.1039/C4MD00255E | ||
CHEMBL3621353 | 130595 | 0 | None | - | 0 | Human | 6.8 | pKi | = | 6.8 | Functional | ChEMBL | 512 | 20 | 3 | 4 | 6.2 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)CC(Br)P(=O)(O)O | 10.1039/C4MD00255E | ||
CHEMBL3623936 | 130595 | 0 | None | - | 0 | Human | 6.8 | pKi | = | 6.8 | Functional | ChEMBL | 512 | 20 | 3 | 4 | 6.2 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)CC(Br)P(=O)(O)O | 10.1039/C4MD00255E | ||
23682233 | 6820 | 0 | None | - | 1 | Human | 6.6 | pIC50 | = | 6.6 | Functional | Guide to Pharmacology | 508 | 20 | 2 | 5 | 5.8 | CCCCCCCCCCCCCCCC(=O)OC[C@H](CC(P(=O)(O[Na])O)Br)O | 18781939 | ||
6991 | 6820 | 0 | None | - | 1 | Human | 6.6 | pIC50 | = | 6.6 | Functional | Guide to Pharmacology | 508 | 20 | 2 | 5 | 5.8 | CCCCCCCCCCCCCCCC(=O)OC[C@H](CC(P(=O)(O[Na])O)Br)O | 18781939 | ||
CHEMBL3621354 | 6820 | 0 | None | - | 1 | Human | 6.6 | pIC50 | = | 6.6 | Functional | Guide to Pharmacology | 508 | 20 | 2 | 5 | 5.8 | CCCCCCCCCCCCCCCC(=O)OC[C@H](CC(P(=O)(O[Na])O)Br)O | 18781939 | ||
2905 | 7177 | 49 | None | -398 | 7 | Human | 5.1 | pIC50 | None | 5.1 | Functional | Guide to Pharmacology | 490 | 7 | 2 | 5 | 6.9 | OC(=O)Cc1ccc(cc1)c1ccc(cc1)c1onc(c1NC(=O)O[C@@H](c1ccccc1Cl)C)C | 20649573 | ||
46240292 | 7177 | 49 | None | -398 | 7 | Human | 5.1 | pIC50 | None | 5.1 | Functional | Guide to Pharmacology | 490 | 7 | 2 | 5 | 6.9 | OC(=O)Cc1ccc(cc1)c1ccc(cc1)c1onc(c1NC(=O)O[C@@H](c1ccccc1Cl)C)C | 20649573 | ||
CHEMBL3621966 | 7177 | 49 | None | -398 | 7 | Human | 5.1 | pIC50 | None | 5.1 | Functional | Guide to Pharmacology | 490 | 7 | 2 | 5 | 6.9 | OC(=O)Cc1ccc(cc1)c1ccc(cc1)c1onc(c1NC(=O)O[C@@H](c1ccccc1Cl)C)C | 20649573 | ||
11132720 | 8403 | 0 | None | -12 | 4 | Human | 5.7 | pIC50 | None | 5.7 | Functional | Guide to Pharmacology | 382 | 11 | 3 | 4 | 4.6 | C/C(=C/COP(=O)(OP(=O)(O)O)O)/CC/C=C(\CCC=C(C)C)/C | 19366702 | ||
2910 | 8403 | 0 | None | -12 | 4 | Human | 5.7 | pIC50 | None | 5.7 | Functional | Guide to Pharmacology | 382 | 11 | 3 | 4 | 4.6 | C/C(=C/COP(=O)(OP(=O)(O)O)O)/CC/C=C(\CCC=C(C)C)/C | 19366702 | ||
DB07780 | 8403 | 0 | None | -12 | 4 | Human | 5.7 | pIC50 | None | 5.7 | Functional | Guide to Pharmacology | 382 | 11 | 3 | 4 | 4.6 | C/C(=C/COP(=O)(OP(=O)(O)O)O)/CC/C=C(\CCC=C(C)C)/C | 19366702 | ||
2911 | 8404 | 0 | None | -29 | 4 | Human | 5.8 | pIC50 | None | 5.8 | Functional | Guide to Pharmacology | 302 | 9 | 2 | 2 | 4.5 | C/C(=C/CC/C(=C\COP(=O)(O)O)/C)/CCC=C(C)C | 19366702 | ||
6440220 | 8404 | 0 | None | -29 | 4 | Human | 5.8 | pIC50 | None | 5.8 | Functional | Guide to Pharmacology | 302 | 9 | 2 | 2 | 4.5 | C/C(=C/CC/C(=C\COP(=O)(O)O)/C)/CCC=C(C)C | 19366702 |
Ligands (move mouse cursor over ligand name to see structure) | Receptor | Assay information | Chemical information | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Similar- ity |
Common name |
GPCRdb ID |
#Vendors |
Reference ligand |
Fold selectivity |
# Tested GPCRs |
Species |
p-value (-log) |
Activity Type |
Activity Relation |
Activity Value |
Assay Type |
Assay Description |
Source |
Mol weight |
Rot Bonds |
H don |
H acc |
LogP |
Smiles |
DOI |
11496444 | 95834 | 0 | None | - | 0 | Human | 8.6 | pEC50 | = | 8.6 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL2335051 | 95834 | 0 | None | - | 0 | Human | 8.6 | pEC50 | = | 8.6 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL2364959 | 95834 | 0 | None | - | 0 | Human | 8.6 | pEC50 | = | 8.6 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | |||
11496444 | 95834 | 0 | None | - | 0 | Human | 8.6 | pEC50 | = | 8.6 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL2335051 | 95834 | 0 | None | - | 0 | Human | 8.6 | pEC50 | = | 8.6 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL2364959 | 95834 | 0 | None | - | 0 | Human | 8.6 | pEC50 | = | 8.6 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | |||
10322404 | 127859 | 0 | None | - | 0 | Human | 8.6 | pEC50 | = | 8.6 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL357053 | 127859 | 0 | None | - | 0 | Human | 8.6 | pEC50 | = | 8.6 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | |||
10322404 | 127859 | 0 | None | - | 0 | Human | 8.6 | pEC50 | = | 8.6 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL357053 | 127859 | 0 | None | - | 0 | Human | 8.6 | pEC50 | = | 8.6 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL5085657 | 221757 | 0 | None | - | 0 | Human | 5.7 | pEC50 | = | 5.7 | Binding | ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)O)C(C)C)C(C)C)C(C)C | nan | |||||
46223906 | 80296 | 0 | None | - | 0 | Human | 8.5 | pEC50 | = | 8.5 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.9 | CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)S)OC | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL2017139 | 80296 | 0 | None | - | 0 | Human | 8.5 | pEC50 | = | 8.5 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.9 | CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)S)OC | 10.1016/j.bmcl.2013.01.002 | |||
46223906 | 80296 | 0 | None | - | 0 | Human | 8.5 | pEC50 | = | 8.5 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.9 | CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)S)OC | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL2017139 | 80296 | 0 | None | - | 0 | Human | 8.5 | pEC50 | = | 8.5 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.9 | CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)S)OC | 10.1016/j.bmcl.2013.01.002 | |||
71720690 | 94299 | 0 | None | - | 0 | Human | 8.5 | pEC50 | = | 8.5 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL2335047 | 94299 | 0 | None | - | 0 | Human | 8.5 | pEC50 | = | 8.5 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | |||
71720690 | 94299 | 0 | None | - | 0 | Human | 8.5 | pEC50 | = | 8.5 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL2335047 | 94299 | 0 | None | - | 0 | Human | 8.5 | pEC50 | = | 8.5 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | |||
11648176 | 94301 | 0 | None | - | 0 | Human | 8.4 | pEC50 | = | 8.4 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOCC(COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL2335052 | 94301 | 0 | None | - | 0 | Human | 8.4 | pEC50 | = | 8.4 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOCC(COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | |||
71569054 | 95843 | 0 | None | - | 0 | Human | 8.4 | pEC50 | = | 8.4 | Binding | ChEMBL | 426 | 21 | 2 | 4 | 5.7 | CCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL2335049 | 95843 | 0 | None | - | 0 | Human | 8.4 | pEC50 | = | 8.4 | Binding | ChEMBL | 426 | 21 | 2 | 4 | 5.7 | CCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL2365070 | 95843 | 0 | None | - | 0 | Human | 8.4 | pEC50 | = | 8.4 | Binding | ChEMBL | 426 | 21 | 2 | 4 | 5.7 | CCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | |||
11648176 | 94301 | 0 | None | - | 0 | Human | 8.4 | pEC50 | = | 8.4 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOCC(COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL2335052 | 94301 | 0 | None | - | 0 | Human | 8.4 | pEC50 | = | 8.4 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOCC(COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | |||
71569054 | 95843 | 0 | None | - | 0 | Human | 8.4 | pEC50 | = | 8.4 | Binding | ChEMBL | 426 | 21 | 2 | 4 | 5.7 | CCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL2335049 | 95843 | 0 | None | - | 0 | Human | 8.4 | pEC50 | = | 8.4 | Binding | ChEMBL | 426 | 21 | 2 | 4 | 5.7 | CCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL2365070 | 95843 | 0 | None | - | 0 | Human | 8.4 | pEC50 | = | 8.4 | Binding | ChEMBL | 426 | 21 | 2 | 4 | 5.7 | CCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | |||
71599962 | 95844 | 0 | None | - | 0 | Human | 8.4 | pEC50 | = | 8.4 | Binding | ChEMBL | 440 | 22 | 2 | 4 | 6.1 | CCCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL2335050 | 95844 | 0 | None | - | 0 | Human | 8.4 | pEC50 | = | 8.4 | Binding | ChEMBL | 440 | 22 | 2 | 4 | 6.1 | CCCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL2365071 | 95844 | 0 | None | - | 0 | Human | 8.4 | pEC50 | = | 8.4 | Binding | ChEMBL | 440 | 22 | 2 | 4 | 6.1 | CCCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | |||
71599962 | 95844 | 0 | None | - | 0 | Human | 8.4 | pEC50 | = | 8.4 | Binding | ChEMBL | 440 | 22 | 2 | 4 | 6.1 | CCCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL2335050 | 95844 | 0 | None | - | 0 | Human | 8.4 | pEC50 | = | 8.4 | Binding | ChEMBL | 440 | 22 | 2 | 4 | 6.1 | CCCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL2365071 | 95844 | 0 | None | - | 0 | Human | 8.4 | pEC50 | = | 8.4 | Binding | ChEMBL | 440 | 22 | 2 | 4 | 6.1 | CCCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | |||
44368508 | 52505 | 0 | None | - | 0 | Human | 8.3 | pEC50 | = | 8.3 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL153043 | 52505 | 0 | None | - | 0 | Human | 8.3 | pEC50 | = | 8.3 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | |||
71719457 | 94300 | 0 | None | - | 0 | Human | 8.3 | pEC50 | = | 8.3 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL2335048 | 94300 | 0 | None | - | 0 | Human | 8.3 | pEC50 | = | 8.3 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | |||
44368508 | 52505 | 0 | None | - | 0 | Human | 8.3 | pEC50 | = | 8.3 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL153043 | 52505 | 0 | None | - | 0 | Human | 8.3 | pEC50 | = | 8.3 | Binding | ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | |||
71719457 | 94300 | 0 | None | - | 0 | Human | 8.3 | pEC50 | = | 8.3 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL2335048 | 94300 | 0 | None | - | 0 | Human | 8.3 | pEC50 | = | 8.3 | Binding | ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | |||
5311263 | 10929 | 22 | None | - | 1 | Human | 8.1 | pEC50 | = | 8.1 | Binding | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL117021 | 10929 | 22 | None | - | 1 | Human | 8.1 | pEC50 | = | 8.1 | Binding | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | |||
5311263 | 10929 | 22 | None | - | 1 | Human | 8.1 | pEC50 | = | 8.1 | Binding | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL117021 | 10929 | 22 | None | - | 1 | Human | 8.1 | pEC50 | = | 8.1 | Binding | ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | |||
6419701 | 132581 | 17 | None | - | 0 | Human | 7.1 | pEC50 | = | 7.1 | Binding | ChEMBL | 410 | 19 | 3 | 5 | 4.5 | CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL364797 | 132581 | 17 | None | - | 0 | Human | 7.1 | pEC50 | = | 7.1 | Binding | ChEMBL | 410 | 19 | 3 | 5 | 4.5 | CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | |||
6419701 | 132581 | 17 | None | - | 0 | Human | 7.1 | pEC50 | = | 7.1 | Binding | ChEMBL | 410 | 19 | 3 | 5 | 4.5 | CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | |||
CHEMBL364797 | 132581 | 17 | None | - | 0 | Human | 7.1 | pEC50 | = | 7.1 | Binding | ChEMBL | 410 | 19 | 3 | 5 | 4.5 | CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | |||
2906 | 9134 | 18 | None | -6 | 4 | Mouse | 7.4 | pKd | = | 7.4 | Binding | Guide to Pharmacology | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 12724320 | |||
5395 | 9134 | 18 | None | -6 | 4 | Mouse | 7.4 | pKd | = | 7.4 | Binding | Guide to Pharmacology | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 12724320 | |||
5497152 | 9134 | 18 | None | -6 | 4 | Mouse | 7.4 | pKd | = | 7.4 | Binding | Guide to Pharmacology | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 12724320 | |||
CHEMBL1222042 | 9134 | 18 | None | -6 | 4 | Mouse | 7.4 | pKd | = | 7.4 | Binding | Guide to Pharmacology | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 12724320 | |||
2906 | 9134 | 18 | None | -6 | 4 | Human | 7.4 | pKd | None | 7.4 | Binding | Guide to Pharmacology | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 12724320 | |||
5395 | 9134 | 18 | None | -6 | 4 | Human | 7.4 | pKd | None | 7.4 | Binding | Guide to Pharmacology | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 12724320 | |||
5497152 | 9134 | 18 | None | -6 | 4 | Human | 7.4 | pKd | None | 7.4 | Binding | Guide to Pharmacology | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 12724320 | |||
CHEMBL1222042 | 9134 | 18 | None | -6 | 4 | Human | 7.4 | pKd | None | 7.4 | Binding | Guide to Pharmacology | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 12724320 |