Ligand source activities (1 row/activity)





Ligands (move mouse cursor over ligand name to see structure) Receptor Assay information Chemical information
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GPCRdb
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ligand
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selectivity
# Tested
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p-value
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DOI





Ligands (move mouse cursor over ligand name to see structure) Receptor Assay information Chemical information
Sel. page Similar-
ity
Common
name
GPCRdb
ID
#Vendors

Reference
ligand
Fold
selectivity
# Tested
GPCRs
Species

p-value
(-log)
Activity
Type
Activity
Relation
Activity
Value
Assay
Type
Assay
Description
Source

Mol
weight
Rot
Bonds
H don

H acc

LogP

Smiles

DOI

259210 148721 22 None - 0 Bovine 4.4 pEC50 = 4.4 Binding
Binding affinity to photoactivated rhodopsin in bovine retinal rod outer-segment membranes assessed as induction of extra receptor MII state stabilization by UV/visible difference spectroscopyBinding affinity to photoactivated rhodopsin in bovine retinal rod outer-segment membranes assessed as induction of extra receptor MII state stabilization by UV/visible difference spectroscopy
ChEMBL 548 5 0 5 5.9 C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)COS(=O)(=O)c1ccc(Br)cc1 10.1021/jm800326q
CHEMBL387152 148721 22 None - 0 Bovine 4.4 pEC50 = 4.4 Binding
Binding affinity to photoactivated rhodopsin in bovine retinal rod outer-segment membranes assessed as induction of extra receptor MII state stabilization by UV/visible difference spectroscopyBinding affinity to photoactivated rhodopsin in bovine retinal rod outer-segment membranes assessed as induction of extra receptor MII state stabilization by UV/visible difference spectroscopy
ChEMBL 548 5 0 5 5.9 C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)COS(=O)(=O)c1ccc(Br)cc1 10.1021/jm800326q
259210 148721 22 None - 0 Bovine 4.8 pIC50 = 4.8 Binding
Inhibition of bovine retinal rod outer-segment photoactivated rhodopsin-transducer interaction by transducer release assayInhibition of bovine retinal rod outer-segment photoactivated rhodopsin-transducer interaction by transducer release assay
ChEMBL 548 5 0 5 5.9 C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)COS(=O)(=O)c1ccc(Br)cc1 10.1021/jm800326q
CHEMBL387152 148721 22 None - 0 Bovine 4.8 pIC50 = 4.8 Binding
Inhibition of bovine retinal rod outer-segment photoactivated rhodopsin-transducer interaction by transducer release assayInhibition of bovine retinal rod outer-segment photoactivated rhodopsin-transducer interaction by transducer release assay
ChEMBL 548 5 0 5 5.9 C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)COS(=O)(=O)c1ccc(Br)cc1 10.1021/jm800326q