Ligand source activities (1 row/activity)
Ligands (move mouse cursor over ligand name to see structure) | Receptor | Assay information | Chemical information | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name |
GPCRdb ID |
#Vendors |
Reference ligand |
Fold selectivity |
# Tested GPCRs |
Species |
p-value (-log) |
Activity Type |
Activity Relation |
Activity Value |
AssayType |
Assay Description |
Source |
Mol weight |
Rot Bonds |
H don |
H acc |
LogP |
Smiles |
DOI |
11648468 | 140211 | 0 | None | - | 1 | strain AD169 | 4.9 | pEC50 | = | 4.9 | Functional | ChEMBL | 433 | 7 | 1 | 2 | 6.5 | Cc1ccc(C(CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)c2ccccc2)cc1 | 10.1021/jm050418d | ||
CHEMBL370577 | 140211 | 0 | None | - | 1 | strain AD169 | 4.9 | pEC50 | = | 4.9 | Functional | ChEMBL | 433 | 7 | 1 | 2 | 6.5 | Cc1ccc(C(CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)c2ccccc2)cc1 | 10.1021/jm050418d | ||
10410351 | 79131 | 0 | None | - | 1 | strain AD169 | 4.9 | pEC50 | = | 4.9 | Functional | ChEMBL | 428 | 7 | 0 | 2 | 6.8 | N#CC(CCCN1CCC(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 | 10.1021/jm050418d | ||
CHEMBL198505 | 79131 | 0 | None | - | 1 | strain AD169 | 4.9 | pEC50 | = | 4.9 | Functional | ChEMBL | 428 | 7 | 0 | 2 | 6.8 | N#CC(CCCN1CCC(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 | 10.1021/jm050418d | ||
10811537 | 78193 | 0 | None | - | 1 | strain AD169 | 4.6 | pEC50 | = | 4.6 | Functional | ChEMBL | 410 | 7 | 1 | 3 | 5.3 | N#CC(CCCN1CCC(O)(c2ccccc2)CC1)(c1ccccc1)c1ccccc1 | 10.1021/jm050418d | ||
CHEMBL195943 | 78193 | 0 | None | - | 1 | strain AD169 | 4.6 | pEC50 | = | 4.6 | Functional | ChEMBL | 410 | 7 | 1 | 3 | 5.3 | N#CC(CCCN1CCC(O)(c2ccccc2)CC1)(c1ccccc1)c1ccccc1 | 10.1021/jm050418d | ||
10670785 | 39894 | 0 | None | - | 1 | strain AD169 | 4.5 | pEC50 | = | 4.5 | Functional | ChEMBL | 440 | 8 | 1 | 4 | 5.3 | COc1ccc(C2(O)CCN(CCCC(C#N)(c3ccccc3)c3ccccc3)CC2)cc1 | 10.1021/jm050418d | ||
CHEMBL141713 | 39894 | 0 | None | - | 1 | strain AD169 | 4.5 | pEC50 | = | 4.5 | Functional | ChEMBL | 440 | 8 | 1 | 4 | 5.3 | COc1ccc(C2(O)CCN(CCCC(C#N)(c3ccccc3)c3ccccc3)CC2)cc1 | 10.1021/jm050418d | ||
9889700 | 125366 | 17 | None | -11 | 4 | strain AD169 | 5.5 | pEC50 | = | 5.5 | Functional | ChEMBL | 444 | 7 | 1 | 3 | 5.9 | N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 | 10.1021/jm050418d | ||
CHEMBL34166 | 125366 | 17 | None | -11 | 4 | strain AD169 | 5.5 | pEC50 | = | 5.5 | Functional | ChEMBL | 444 | 7 | 1 | 3 | 5.9 | N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 | 10.1021/jm050418d | ||
10526132 | 79252 | 0 | None | 1 | 2 | strain AD169 | 5.4 | pEC50 | = | 5.4 | Functional | ChEMBL | 419 | 7 | 1 | 2 | 6.2 | OC1(c2ccc(Cl)cc2)CCN(CCCC(c2ccccc2)c2ccccc2)CC1 | 10.1021/jm050418d | ||
CHEMBL142004 | 79252 | 0 | None | 1 | 2 | strain AD169 | 5.4 | pEC50 | = | 5.4 | Functional | ChEMBL | 419 | 7 | 1 | 2 | 6.2 | OC1(c2ccc(Cl)cc2)CCN(CCCC(c2ccccc2)c2ccccc2)CC1 | 10.1021/jm050418d | ||
CHEMBL198935 | 79252 | 0 | None | 1 | 2 | strain AD169 | 5.4 | pEC50 | = | 5.4 | Functional | ChEMBL | 419 | 7 | 1 | 2 | 6.2 | OC1(c2ccc(Cl)cc2)CCN(CCCC(c2ccccc2)c2ccccc2)CC1 | 10.1021/jm050418d | ||
11719018 | 79140 | 0 | None | - | 1 | strain AD169 | 5.0 | pEC50 | = | 5.0 | Functional | ChEMBL | 433 | 7 | 1 | 2 | 6.5 | Cc1ccccc1C(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1 | 10.1021/jm050418d | ||
CHEMBL198553 | 79140 | 0 | None | - | 1 | strain AD169 | 5.0 | pEC50 | = | 5.0 | Functional | ChEMBL | 433 | 7 | 1 | 2 | 6.5 | Cc1ccccc1C(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1 | 10.1021/jm050418d |
Ligands (move mouse cursor over ligand name to see structure) | Receptor | Assay information | Chemical information | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Similar- ity |
Common name |
GPCRdb ID |
#Vendors |
Reference ligand |
Fold selectivity |
# Tested GPCRs |
Species |
p-value (-log) |
Activity Type |
Activity Relation |
Activity Value |
Assay Type |
Assay Description |
Source |
Mol weight |
Rot Bonds |
H don |
H acc |
LogP |
Smiles |
DOI |
56679132 | 71941 | 0 | None | - | 0 | strain AD169 | 6.0 | pEC50 | = | 6 | Binding | ChEMBL | 281 | 3 | 1 | 2 | 3.0 | CC1(CCO)Cc2ccccc2C(=O)N1c1ccccc1 | 10.1016/j.bmcl.2014.06.082 | |||
CHEMBL1824272 | 71941 | 0 | None | - | 0 | strain AD169 | 6.0 | pEC50 | = | 6 | Binding | ChEMBL | 281 | 3 | 1 | 2 | 3.0 | CC1(CCO)Cc2ccccc2C(=O)N1c1ccccc1 | 10.1016/j.bmcl.2014.06.082 | |||
56679132 | 71941 | 0 | None | - | 0 | strain AD169 | 6.0 | pEC50 | = | 6.0 | Binding | ChEMBL | 281 | 3 | 1 | 2 | 3.0 | CC1(CCO)Cc2ccccc2C(=O)N1c1ccccc1 | 10.1016/j.bmcl.2014.06.082 | |||
CHEMBL1824272 | 71941 | 0 | None | - | 0 | strain AD169 | 6.0 | pEC50 | = | 6.0 | Binding | ChEMBL | 281 | 3 | 1 | 2 | 3.0 | CC1(CCO)Cc2ccccc2C(=O)N1c1ccccc1 | 10.1016/j.bmcl.2014.06.082 | |||
56668956 | 71939 | 0 | None | - | 0 | strain AD169 | 5.8 | pEC50 | = | 5.8 | Binding | ChEMBL | 415 | 13 | 1 | 3 | 4.3 | CCCCCCCCCC(=O)N(CCN(C)C)CC1(C)Cc2ccccc2C(=O)N1 | 10.1016/j.bmcl.2014.06.082 | |||
CHEMBL1824269 | 71939 | 0 | None | - | 0 | strain AD169 | 5.8 | pEC50 | = | 5.8 | Binding | ChEMBL | 415 | 13 | 1 | 3 | 4.3 | CCCCCCCCCC(=O)N(CCN(C)C)CC1(C)Cc2ccccc2C(=O)N1 | 10.1016/j.bmcl.2014.06.082 | |||
56668956 | 71939 | 0 | None | - | 0 | strain AD169 | 5.8 | pEC50 | = | 5.8 | Binding | ChEMBL | 415 | 13 | 1 | 3 | 4.3 | CCCCCCCCCC(=O)N(CCN(C)C)CC1(C)Cc2ccccc2C(=O)N1 | 10.1016/j.bmcl.2014.06.082 | |||
CHEMBL1824269 | 71939 | 0 | None | - | 0 | strain AD169 | 5.8 | pEC50 | = | 5.8 | Binding | ChEMBL | 415 | 13 | 1 | 3 | 4.3 | CCCCCCCCCC(=O)N(CCN(C)C)CC1(C)Cc2ccccc2C(=O)N1 | 10.1016/j.bmcl.2014.06.082 | |||
56682429 | 71942 | 0 | None | - | 0 | strain AD169 | 5.5 | pEC50 | = | 5.5 | Binding | ChEMBL | 413 | 6 | 0 | 3 | 4.4 | CC1(COC(=O)Cc2ccccc2)Cc2ccccc2CN1C(=O)Cc1ccccc1 | 10.1016/j.bmcl.2014.06.082 | |||
CHEMBL1824275 | 71942 | 0 | None | - | 0 | strain AD169 | 5.5 | pEC50 | = | 5.5 | Binding | ChEMBL | 413 | 6 | 0 | 3 | 4.4 | CC1(COC(=O)Cc2ccccc2)Cc2ccccc2CN1C(=O)Cc1ccccc1 | 10.1016/j.bmcl.2014.06.082 | |||
56682429 | 71942 | 0 | None | - | 0 | strain AD169 | 5.5 | pEC50 | = | 5.5 | Binding | ChEMBL | 413 | 6 | 0 | 3 | 4.4 | CC1(COC(=O)Cc2ccccc2)Cc2ccccc2CN1C(=O)Cc1ccccc1 | 10.1016/j.bmcl.2014.06.082 | |||
CHEMBL1824275 | 71942 | 0 | None | - | 0 | strain AD169 | 5.5 | pEC50 | = | 5.5 | Binding | ChEMBL | 413 | 6 | 0 | 3 | 4.4 | CC1(COC(=O)Cc2ccccc2)Cc2ccccc2CN1C(=O)Cc1ccccc1 | 10.1016/j.bmcl.2014.06.082 | |||
4106 | 9280 | 22 | None | - | 33 | strain AD169 | 6.5 | pEC50 | = | 6.5 | Binding | ChEMBL | 356 | 2 | 0 | 4 | 4.4 | CSc1ccc2c(c1)C(Cc1c(S2)cccc1)N1CCN(CC1)C | 10.1016/j.bmcl.2014.06.082 | |||
5358812 | 9280 | 22 | None | - | 33 | strain AD169 | 6.5 | pEC50 | = | 6.5 | Binding | ChEMBL | 356 | 2 | 0 | 4 | 4.4 | CSc1ccc2c(c1)C(Cc1c(S2)cccc1)N1CCN(CC1)C | 10.1016/j.bmcl.2014.06.082 | |||
89 | 9280 | 22 | None | - | 33 | strain AD169 | 6.5 | pEC50 | = | 6.5 | Binding | ChEMBL | 356 | 2 | 0 | 4 | 4.4 | CSc1ccc2c(c1)C(Cc1c(S2)cccc1)N1CCN(CC1)C | 10.1016/j.bmcl.2014.06.082 | |||
CHEMBL93240 | 9280 | 22 | None | - | 33 | strain AD169 | 6.5 | pEC50 | = | 6.5 | Binding | ChEMBL | 356 | 2 | 0 | 4 | 4.4 | CSc1ccc2c(c1)C(Cc1c(S2)cccc1)N1CCN(CC1)C | 10.1016/j.bmcl.2014.06.082 | |||
4106 | 9280 | 22 | None | - | 33 | strain AD169 | 6.5 | pEC50 | = | 6.5 | Binding | ChEMBL | 356 | 2 | 0 | 4 | 4.4 | CSc1ccc2c(c1)C(Cc1c(S2)cccc1)N1CCN(CC1)C | 10.1016/j.bmcl.2014.06.082 | |||
5358812 | 9280 | 22 | None | - | 33 | strain AD169 | 6.5 | pEC50 | = | 6.5 | Binding | ChEMBL | 356 | 2 | 0 | 4 | 4.4 | CSc1ccc2c(c1)C(Cc1c(S2)cccc1)N1CCN(CC1)C | 10.1016/j.bmcl.2014.06.082 | |||
89 | 9280 | 22 | None | - | 33 | strain AD169 | 6.5 | pEC50 | = | 6.5 | Binding | ChEMBL | 356 | 2 | 0 | 4 | 4.4 | CSc1ccc2c(c1)C(Cc1c(S2)cccc1)N1CCN(CC1)C | 10.1016/j.bmcl.2014.06.082 | |||
CHEMBL93240 | 9280 | 22 | None | - | 33 | strain AD169 | 6.5 | pEC50 | = | 6.5 | Binding | ChEMBL | 356 | 2 | 0 | 4 | 4.4 | CSc1ccc2c(c1)C(Cc1c(S2)cccc1)N1CCN(CC1)C | 10.1016/j.bmcl.2014.06.082 | |||
56665519 | 71940 | 0 | None | - | 0 | strain AD169 | 5.4 | pEC50 | = | 5.4 | Binding | ChEMBL | 267 | 2 | 1 | 2 | 2.6 | CC1(CO)Cc2ccccc2C(=O)N1c1ccccc1 | 10.1016/j.bmcl.2014.06.082 | |||
CHEMBL1824270 | 71940 | 0 | None | - | 0 | strain AD169 | 5.4 | pEC50 | = | 5.4 | Binding | ChEMBL | 267 | 2 | 1 | 2 | 2.6 | CC1(CO)Cc2ccccc2C(=O)N1c1ccccc1 | 10.1016/j.bmcl.2014.06.082 | |||
56665519 | 71940 | 0 | None | - | 0 | strain AD169 | 5.4 | pEC50 | = | 5.4 | Binding | ChEMBL | 267 | 2 | 1 | 2 | 2.6 | CC1(CO)Cc2ccccc2C(=O)N1c1ccccc1 | 10.1016/j.bmcl.2014.06.082 | |||
CHEMBL1824270 | 71940 | 0 | None | - | 0 | strain AD169 | 5.4 | pEC50 | = | 5.4 | Binding | ChEMBL | 267 | 2 | 1 | 2 | 2.6 | CC1(CO)Cc2ccccc2C(=O)N1c1ccccc1 | 10.1016/j.bmcl.2014.06.082 | |||
9889700 | 125366 | 17 | None | - | 1 | strain AD169 | 5.4 | pEC50 | = | 5.4 | Binding | ChEMBL | 444 | 7 | 1 | 3 | 5.9 | N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 | 10.1016/j.bmcl.2014.06.082 | |||
CHEMBL34166 | 125366 | 17 | None | - | 1 | strain AD169 | 5.4 | pEC50 | = | 5.4 | Binding | ChEMBL | 444 | 7 | 1 | 3 | 5.9 | N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 | 10.1016/j.bmcl.2014.06.082 | |||
9889700 | 125366 | 17 | None | - | 1 | strain AD169 | 5.3 | pEC50 | = | 5.3 | Binding | ChEMBL | 444 | 7 | 1 | 3 | 5.9 | N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 | 10.1016/j.bmcl.2014.06.082 | |||
CHEMBL34166 | 125366 | 17 | None | - | 1 | strain AD169 | 5.3 | pEC50 | = | 5.3 | Binding | ChEMBL | 444 | 7 | 1 | 3 | 5.9 | N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 | 10.1016/j.bmcl.2014.06.082 | |||
10410351 | 79131 | 0 | None | - | 0 | strain AD169 | 5.0 | pIC50 | = | 5.0 | Binding | ChEMBL | 428 | 7 | 0 | 2 | 6.8 | N#CC(CCCN1CCC(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 | 10.1021/jm050418d | |||
CHEMBL198505 | 79131 | 0 | None | - | 0 | strain AD169 | 5.0 | pIC50 | = | 5.0 | Binding | ChEMBL | 428 | 7 | 0 | 2 | 6.8 | N#CC(CCCN1CCC(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 | 10.1021/jm050418d | |||
11547305 | 148154 | 0 | None | - | 0 | strain AD169 | 4.9 | pIC50 | = | 4.9 | Binding | ChEMBL | 433 | 7 | 1 | 2 | 6.5 | Cc1cccc(C(CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)c2ccccc2)c1 | 10.1021/jm050418d | |||
CHEMBL383822 | 148154 | 0 | None | - | 0 | strain AD169 | 4.9 | pIC50 | = | 4.9 | Binding | ChEMBL | 433 | 7 | 1 | 2 | 6.5 | Cc1cccc(C(CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)c2ccccc2)c1 | 10.1021/jm050418d | |||
11609863 | 23618 | 0 | None | - | 0 | strain AD169 | 4.8 | pIC50 | = | 4.8 | Binding | ChEMBL | 343 | 6 | 1 | 2 | 4.6 | OC1(c2ccc(Cl)cc2)CCN(CCCCc2ccccc2)CC1 | 10.1021/jm050418d | |||
CHEMBL124813 | 23618 | 0 | None | - | 0 | strain AD169 | 4.8 | pIC50 | = | 4.8 | Binding | ChEMBL | 343 | 6 | 1 | 2 | 4.6 | OC1(c2ccc(Cl)cc2)CCN(CCCCc2ccccc2)CC1 | 10.1021/jm050418d | |||
11705066 | 78996 | 0 | None | - | 0 | strain AD169 | 4.8 | pIC50 | = | 4.8 | Binding | ChEMBL | 449 | 8 | 1 | 3 | 6.2 | COc1ccc(C(CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)c2ccccc2)cc1 | 10.1021/jm050418d | |||
CHEMBL198111 | 78996 | 0 | None | - | 0 | strain AD169 | 4.8 | pIC50 | = | 4.8 | Binding | ChEMBL | 449 | 8 | 1 | 3 | 6.2 | COc1ccc(C(CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)c2ccccc2)cc1 | 10.1021/jm050418d | |||
11569984 | 79081 | 0 | None | - | 0 | strain AD169 | 4.8 | pIC50 | = | 4.8 | Binding | ChEMBL | 487 | 7 | 1 | 2 | 7.5 | OC1(c2ccc(Cl)cc2)CCN(CCCC(c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1 | 10.1021/jm050418d | |||
CHEMBL198332 | 79081 | 0 | None | - | 0 | strain AD169 | 4.8 | pIC50 | = | 4.8 | Binding | ChEMBL | 487 | 7 | 1 | 2 | 7.5 | OC1(c2ccc(Cl)cc2)CCN(CCCC(c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1 | 10.1021/jm050418d | |||
11525302 | 79153 | 0 | None | - | 0 | strain AD169 | 4.8 | pIC50 | = | 4.8 | Binding | ChEMBL | 453 | 7 | 1 | 2 | 6.9 | OC1(c2ccc(Cl)cc2)CCN(CCCC(c2ccccc2)c2ccc(Cl)cc2)CC1 | 10.1021/jm050418d | |||
CHEMBL198614 | 79153 | 0 | None | - | 0 | strain AD169 | 4.8 | pIC50 | = | 4.8 | Binding | ChEMBL | 453 | 7 | 1 | 2 | 6.9 | OC1(c2ccc(Cl)cc2)CCN(CCCC(c2ccccc2)c2ccc(Cl)cc2)CC1 | 10.1021/jm050418d | |||
11642194 | 147923 | 0 | None | - | 0 | strain AD169 | 4.8 | pIC50 | = | 4.8 | Binding | ChEMBL | 487 | 7 | 1 | 2 | 7.5 | OC1(c2ccc(Cl)cc2)CCN(CCCC(c2ccc(Cl)cc2)c2ccc(Cl)cc2)CC1 | 10.1021/jm050418d | |||
CHEMBL382760 | 147923 | 0 | None | - | 0 | strain AD169 | 4.8 | pIC50 | = | 4.8 | Binding | ChEMBL | 487 | 7 | 1 | 2 | 7.5 | OC1(c2ccc(Cl)cc2)CCN(CCCC(c2ccc(Cl)cc2)c2ccc(Cl)cc2)CC1 | 10.1021/jm050418d | |||
10576989 | 78862 | 0 | None | - | 0 | strain AD169 | 4.7 | pIC50 | = | 4.7 | Binding | ChEMBL | 488 | 7 | 1 | 3 | 6.0 | N#CC(CCCN1CCC(O)(c2ccc(Br)cc2)CC1)(c1ccccc1)c1ccccc1 | 10.1021/jm050418d | |||
CHEMBL197749 | 78862 | 0 | None | - | 0 | strain AD169 | 4.7 | pIC50 | = | 4.7 | Binding | ChEMBL | 488 | 7 | 1 | 3 | 6.0 | N#CC(CCCN1CCC(O)(c2ccc(Br)cc2)CC1)(c1ccccc1)c1ccccc1 | 10.1021/jm050418d | |||
11648468 | 140211 | 0 | None | - | 0 | strain AD169 | 4.5 | pIC50 | = | 4.5 | Binding | ChEMBL | 433 | 7 | 1 | 2 | 6.5 | Cc1ccc(C(CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)c2ccccc2)cc1 | 10.1021/jm050418d | |||
CHEMBL370577 | 140211 | 0 | None | - | 0 | strain AD169 | 4.5 | pIC50 | = | 4.5 | Binding | ChEMBL | 433 | 7 | 1 | 2 | 6.5 | Cc1ccc(C(CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)c2ccccc2)cc1 | 10.1021/jm050418d | |||
11510165 | 79065 | 0 | None | - | 0 | strain AD169 | 4.5 | pIC50 | = | 4.5 | Binding | ChEMBL | 390 | 8 | 0 | 4 | 4.6 | CCOC(=O)C1CCN(CCCC(C#N)(c2ccccc2)c2ccccc2)CC1 | 10.1021/jm050418d | |||
CHEMBL198308 | 79065 | 0 | None | - | 0 | strain AD169 | 4.5 | pIC50 | = | 4.5 | Binding | ChEMBL | 390 | 8 | 0 | 4 | 4.6 | CCOC(=O)C1CCN(CCCC(C#N)(c2ccccc2)c2ccccc2)CC1 | 10.1021/jm050418d | |||
10811537 | 78193 | 0 | None | - | 0 | strain AD169 | 4.5 | pIC50 | = | 4.5 | Binding | ChEMBL | 410 | 7 | 1 | 3 | 5.3 | N#CC(CCCN1CCC(O)(c2ccccc2)CC1)(c1ccccc1)c1ccccc1 | 10.1021/jm050418d | |||
CHEMBL195943 | 78193 | 0 | None | - | 0 | strain AD169 | 4.5 | pIC50 | = | 4.5 | Binding | ChEMBL | 410 | 7 | 1 | 3 | 5.3 | N#CC(CCCN1CCC(O)(c2ccccc2)CC1)(c1ccccc1)c1ccccc1 | 10.1021/jm050418d | |||
11634351 | 79071 | 0 | None | - | 0 | strain AD169 | 4.4 | pIC50 | = | 4.4 | Binding | ChEMBL | 478 | 7 | 1 | 3 | 6.6 | N#CC(CCCN1CCC(O)(c2ccc(Cl)c(Cl)c2)CC1)(c1ccccc1)c1ccccc1 | 10.1021/jm050418d | |||
CHEMBL198313 | 79071 | 0 | None | - | 0 | strain AD169 | 4.4 | pIC50 | = | 4.4 | Binding | ChEMBL | 478 | 7 | 1 | 3 | 6.6 | N#CC(CCCN1CCC(O)(c2ccc(Cl)c(Cl)c2)CC1)(c1ccccc1)c1ccccc1 | 10.1021/jm050418d | |||
11584791 | 140335 | 0 | None | - | 0 | strain AD169 | 4.3 | pIC50 | = | 4.3 | Binding | ChEMBL | 512 | 7 | 1 | 3 | 6.9 | N#CC(CCCN1CCC(O)(c2ccc(Cl)c(C(F)(F)F)c2)CC1)(c1ccccc1)c1ccccc1 | 10.1021/jm050418d | |||
CHEMBL371031 | 140335 | 0 | None | - | 0 | strain AD169 | 4.3 | pIC50 | = | 4.3 | Binding | ChEMBL | 512 | 7 | 1 | 3 | 6.9 | N#CC(CCCN1CCC(O)(c2ccc(Cl)c(C(F)(F)F)c2)CC1)(c1ccccc1)c1ccccc1 | 10.1021/jm050418d | |||
11719018 | 79140 | 0 | None | - | 0 | strain AD169 | 5.3 | pIC50 | = | 5.3 | Binding | ChEMBL | 433 | 7 | 1 | 2 | 6.5 | Cc1ccccc1C(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1 | 10.1021/jm050418d | |||
CHEMBL198553 | 79140 | 0 | None | - | 0 | strain AD169 | 5.3 | pIC50 | = | 5.3 | Binding | ChEMBL | 433 | 7 | 1 | 2 | 6.5 | Cc1ccccc1C(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1 | 10.1021/jm050418d | |||
11698316 | 78847 | 0 | None | - | 0 | strain AD169 | 4.2 | pIC50 | = | 4.2 | Binding | ChEMBL | 424 | 7 | 1 | 3 | 5.6 | Cc1ccc(C2(O)CCN(CCCC(C#N)(c3ccccc3)c3ccccc3)CC2)cc1 | 10.1021/jm050418d | |||
CHEMBL197694 | 78847 | 0 | None | - | 0 | strain AD169 | 4.2 | pIC50 | = | 4.2 | Binding | ChEMBL | 424 | 7 | 1 | 3 | 5.6 | Cc1ccc(C2(O)CCN(CCCC(C#N)(c3ccccc3)c3ccccc3)CC2)cc1 | 10.1021/jm050418d | |||
11674616 | 78840 | 0 | None | - | 0 | strain AD169 | 4.2 | pIC50 | = | 4.2 | Binding | ChEMBL | 345 | 6 | 1 | 3 | 4.1 | OC1(c2ccc(Cl)cc2)CCN(CCCOc2ccccc2)CC1 | 10.1021/jm050418d | |||
CHEMBL197675 | 78840 | 0 | None | - | 0 | strain AD169 | 4.2 | pIC50 | = | 4.2 | Binding | ChEMBL | 345 | 6 | 1 | 3 | 4.1 | OC1(c2ccc(Cl)cc2)CCN(CCCOc2ccccc2)CC1 | 10.1021/jm050418d | |||
11626763 | 79183 | 0 | None | - | 0 | strain AD169 | 4.2 | pIC50 | = | 4.2 | Binding | ChEMBL | 424 | 8 | 1 | 3 | 5.3 | N#CC(CCCN1CCC(O)(Cc2ccccc2)CC1)(c1ccccc1)c1ccccc1 | 10.1021/jm050418d | |||
CHEMBL198721 | 79183 | 0 | None | - | 0 | strain AD169 | 4.2 | pIC50 | = | 4.2 | Binding | ChEMBL | 424 | 8 | 1 | 3 | 5.3 | N#CC(CCCN1CCC(O)(Cc2ccccc2)CC1)(c1ccccc1)c1ccccc1 | 10.1021/jm050418d | |||
10526132 | 79252 | 0 | None | - | 1 | strain AD169 | 5.2 | pIC50 | = | 5.2 | Binding | ChEMBL | 419 | 7 | 1 | 2 | 6.2 | OC1(c2ccc(Cl)cc2)CCN(CCCC(c2ccccc2)c2ccccc2)CC1 | 10.1021/jm050418d | |||
CHEMBL142004 | 79252 | 0 | None | - | 1 | strain AD169 | 5.2 | pIC50 | = | 5.2 | Binding | ChEMBL | 419 | 7 | 1 | 2 | 6.2 | OC1(c2ccc(Cl)cc2)CCN(CCCC(c2ccccc2)c2ccccc2)CC1 | 10.1021/jm050418d | |||
CHEMBL198935 | 79252 | 0 | None | - | 1 | strain AD169 | 5.2 | pIC50 | = | 5.2 | Binding | ChEMBL | 419 | 7 | 1 | 2 | 6.2 | OC1(c2ccc(Cl)cc2)CCN(CCCC(c2ccccc2)c2ccccc2)CC1 | 10.1021/jm050418d | |||
10670785 | 39894 | 0 | None | - | 1 | strain AD169 | 4.1 | pIC50 | = | 4.1 | Binding | ChEMBL | 440 | 8 | 1 | 4 | 5.3 | COc1ccc(C2(O)CCN(CCCC(C#N)(c3ccccc3)c3ccccc3)CC2)cc1 | 10.1021/jm050418d | |||
CHEMBL141713 | 39894 | 0 | None | - | 1 | strain AD169 | 4.1 | pIC50 | = | 4.1 | Binding | ChEMBL | 440 | 8 | 1 | 4 | 5.3 | COc1ccc(C2(O)CCN(CCCC(C#N)(c3ccccc3)c3ccccc3)CC2)cc1 | 10.1021/jm050418d | |||
9889700 | 125366 | 17 | None | - | 1 | strain AD169 | 5.0 | pIC50 | = | 5.0 | Binding | ChEMBL | 444 | 7 | 1 | 3 | 5.9 | N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 | 10.1021/jm050418d | |||
CHEMBL34166 | 125366 | 17 | None | - | 1 | strain AD169 | 5.0 | pIC50 | = | 5.0 | Binding | ChEMBL | 444 | 7 | 1 | 3 | 5.9 | N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 | 10.1021/jm050418d |