Ligand source activities (1 row/activity)
Ligands (move mouse cursor over ligand name to see structure) | Receptor | Assay information | Chemical information | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name |
GPCRdb ID |
#Vendors |
Reference ligand |
Fold selectivity |
# Tested GPCRs |
Species |
p-value (-log) |
Activity Type |
Activity Relation |
Activity Value |
AssayType |
Assay Description |
Source |
Mol weight |
Rot Bonds |
H don |
H acc |
LogP |
Smiles |
DOI |
16158474 | 217727 | 17 | None | - | 1 | Human | 10.1 | pEC50 | = | 10.1 | Functional | ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@H](C(N)=O)C(C)C | 10.1016/j.bmcl.2010.08.062 | ||||
CHEMBL3039582 | 217727 | 17 | None | - | 1 | Human | 10.1 | pEC50 | = | 10.1 | Functional | ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@H](C(N)=O)C(C)C | 10.1016/j.bmcl.2010.08.062 | ||||
CHEMBL1256314 | 215444 | 0 | None | - | 1 | Human | 10.0 | pEC50 | = | 10 | Functional | ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N1)C(=O)N[C@H](C(N)=O)C(C)C | 10.1016/j.bmcl.2010.08.062 | ||||
16158474 | 217727 | 17 | None | - | 1 | Human | 8.0 | pEC50 | = | 8.0 | Functional | Drug Central | None | None | None | CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@H](C(N)=O)C(C)C | None | ||||
CHEMBL3039582 | 217727 | 17 | None | - | 1 | Human | 8.0 | pEC50 | = | 8.0 | Functional | Drug Central | None | None | None | CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@H](C(N)=O)C(C)C | None | ||||
1155 | 10345 | 0 | None | 5 | 7 | Human | 9.7 | pEC50 | = | 9.7 | Functional | Guide to Pharmacology | None | None | None | None | 7612008 | ||||
16129665 | 10345 | 0 | None | 5 | 7 | Human | 9.7 | pEC50 | = | 9.7 | Functional | Guide to Pharmacology | None | None | None | None | 7612008 | ||||
3643 | 10345 | 0 | None | 5 | 7 | Human | 9.7 | pEC50 | = | 9.7 | Functional | Guide to Pharmacology | None | None | None | None | 7612008 | ||||
CHEMBL1201488 | 10345 | 0 | None | 5 | 7 | Human | 9.7 | pEC50 | = | 9.7 | Functional | Guide to Pharmacology | None | None | None | None | 7612008 | ||||
DB00021 | 10345 | 0 | None | 5 | 7 | Human | 9.7 | pEC50 | = | 9.7 | Functional | Guide to Pharmacology | None | None | None | None | 7612008 | ||||
1152 | 10767 | 16 | None | -3090 | 8 | Human | 5.4 | pIC50 | = | 5.4 | Functional | Guide to Pharmacology | None | None | None | None | 1646711 | ||||
16129679 | 10767 | 16 | None | -3090 | 8 | Human | 5.4 | pIC50 | = | 5.4 | Functional | Guide to Pharmacology | None | None | None | None | 1646711 | ||||
53395115 | 10767 | 16 | None | -3090 | 8 | Human | 5.4 | pIC50 | = | 5.4 | Functional | Guide to Pharmacology | None | None | None | None | 1646711 | ||||
91898389 | 10767 | 16 | None | -3090 | 8 | Human | 5.4 | pIC50 | = | 5.4 | Functional | Guide to Pharmacology | None | None | None | None | 1646711 | ||||
CHEMBL1981592 | 10767 | 16 | None | -3090 | 8 | Human | 5.4 | pIC50 | = | 5.4 | Functional | Guide to Pharmacology | None | None | None | None | 1646711 | ||||
1156 | 10348 | 0 | None | - | 1 | Rat | 5.0 | pIC50 | None | 5 | Functional | Guide to Pharmacology | None | None | None | None | 1646711 |
Ligands (move mouse cursor over ligand name to see structure) | Receptor | Assay information | Chemical information | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Similar- ity |
Common name |
GPCRdb ID |
#Vendors |
Reference ligand |
Fold selectivity |
# Tested GPCRs |
Species |
p-value (-log) |
Activity Type |
Activity Relation |
Activity Value |
Assay Type |
Assay Description |
Source |
Mol weight |
Rot Bonds |
H don |
H acc |
LogP |
Smiles |
DOI |
CHEMBL1256314 | 215444 | 0 | None | - | 1 | Human | 8.0 | pKi | = | 8.0 | Binding | ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N1)C(=O)N[C@H](C(N)=O)C(C)C | 10.1016/j.bmcl.2010.08.062 | |||||
16158474 | 217727 | 17 | None | - | 1 | Human | 8.5 | pKi | = | 8.5 | Binding | ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@H](C(N)=O)C(C)C | 10.1016/j.bmcl.2010.08.062 | |||||
CHEMBL3039582 | 217727 | 17 | None | - | 1 | Human | 8.5 | pKi | = | 8.5 | Binding | ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@H](C(N)=O)C(C)C | 10.1016/j.bmcl.2010.08.062 | |||||
1152 | 10767 | 16 | None | - | 4 | Rat | 6.2 | pIC50 | = | 6.2 | Binding | Guide to Pharmacology | None | None | None | None | 9437714 | |||||
16129679 | 10767 | 16 | None | - | 4 | Rat | 6.2 | pIC50 | = | 6.2 | Binding | Guide to Pharmacology | None | None | None | None | 9437714 | |||||
53395115 | 10767 | 16 | None | - | 4 | Rat | 6.2 | pIC50 | = | 6.2 | Binding | Guide to Pharmacology | None | None | None | None | 9437714 | |||||
91898389 | 10767 | 16 | None | - | 4 | Rat | 6.2 | pIC50 | = | 6.2 | Binding | Guide to Pharmacology | None | None | None | None | 9437714 | |||||
CHEMBL1981592 | 10767 | 16 | None | - | 4 | Rat | 6.2 | pIC50 | = | 6.2 | Binding | Guide to Pharmacology | None | None | None | None | 9437714 | |||||
3293 | 7256 | 0 | None | - | 0 | Rat | 7.7 | pIC50 | = | 7.7 | Binding | Guide to Pharmacology | None | None | None | None | 9437714 | |||||
1155 | 10345 | 0 | None | 3162 | 2 | Rat | 9.0 | pIC50 | = | 9 | Binding | Guide to Pharmacology | None | None | None | None | 9437714 | |||||
16129665 | 10345 | 0 | None | 3162 | 2 | Rat | 9.0 | pIC50 | = | 9 | Binding | Guide to Pharmacology | None | None | None | None | 9437714 | |||||
3643 | 10345 | 0 | None | 3162 | 2 | Rat | 9.0 | pIC50 | = | 9 | Binding | Guide to Pharmacology | None | None | None | None | 9437714 | |||||
CHEMBL1201488 | 10345 | 0 | None | 3162 | 2 | Rat | 9.0 | pIC50 | = | 9 | Binding | Guide to Pharmacology | None | None | None | None | 9437714 | |||||
DB00021 | 10345 | 0 | None | 3162 | 2 | Rat | 9.0 | pIC50 | = | 9 | Binding | Guide to Pharmacology | None | None | None | None | 9437714 | |||||
3755 | 7711 | 0 | None | - | 1 | Human | 5.3 | pKi | = | 5.3 | Binding | Guide to Pharmacology | None | None | None | None | 1702423 | |||||
1155 | 10345 | 0 | None | 3162 | 2 | Rat | 8.5 | pKi | = | 8.5 | Binding | Guide to Pharmacology | None | None | None | None | 1646711 | |||||
16129665 | 10345 | 0 | None | 3162 | 2 | Rat | 8.5 | pKi | = | 8.5 | Binding | Guide to Pharmacology | None | None | None | None | 1646711 | |||||
3643 | 10345 | 0 | None | 3162 | 2 | Rat | 8.5 | pKi | = | 8.5 | Binding | Guide to Pharmacology | None | None | None | None | 1646711 | |||||
CHEMBL1201488 | 10345 | 0 | None | 3162 | 2 | Rat | 8.5 | pKi | = | 8.5 | Binding | Guide to Pharmacology | None | None | None | None | 1646711 | |||||
DB00021 | 10345 | 0 | None | 3162 | 2 | Rat | 8.5 | pKi | = | 8.5 | Binding | Guide to Pharmacology | None | None | None | None | 1646711 | |||||
2943 | 10346 | 0 | None | - | 1 | Rat | 8.5 | pKi | = | 8.5 | Binding | Guide to Pharmacology | None | None | None | None | 10383421 | |||||
2943 | 10346 | 0 | None | - | 1 | Rat | 8.5 | pKi | = | 8.5 | Binding | Guide to Pharmacology | None | None | None | None | 9694908 |