Ligand source activities (1 row/activity)
Ligands (move mouse cursor over ligand name to see structure) | Receptor | Assay information | Chemical information | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name |
GPCRdb ID |
#Vendors |
Reference ligand |
Fold selectivity |
# Tested GPCRs |
Species |
p-value (-log) |
Activity Type |
Activity Relation |
Activity Value |
AssayType |
Assay Description |
Source |
Mol weight |
Rot Bonds |
H don |
H acc |
LogP |
Smiles |
DOI |
5572 | 1928 | 0 | None | - | 1 | Rat | 7.6 | pA2 | = | 7.6 | Functional | Guide to Pharmacology | None | None | None | None | None | ||||
129631922 | 3781 | 13 | None | -34 | 4 | Rat | 8.2 | pIC50 | = | 8.2 | Functional | Drug Central | None | None | None | None | None | ||||
132274287 | 3781 | 13 | None | -34 | 4 | Rat | 8.2 | pIC50 | = | 8.2 | Functional | Drug Central | None | None | None | None | None | ||||
132451761 | 3781 | 13 | None | -34 | 4 | Rat | 8.2 | pIC50 | = | 8.2 | Functional | Drug Central | None | None | None | None | None | ||||
155817470 | 3781 | 13 | None | -34 | 4 | Rat | 8.2 | pIC50 | = | 8.2 | Functional | Drug Central | None | None | None | None | None | ||||
16132393 | 3781 | 13 | None | -34 | 4 | Rat | 8.2 | pIC50 | = | 8.2 | Functional | Drug Central | None | None | None | None | None | ||||
16133850 | 3781 | 13 | None | -34 | 4 | Rat | 8.2 | pIC50 | = | 8.2 | Functional | Drug Central | None | None | None | None | None | ||||
4448 | 3781 | 13 | None | -34 | 4 | Rat | 8.2 | pIC50 | = | 8.2 | Functional | Drug Central | None | None | None | None | None | ||||
4514 | 3781 | 13 | None | -34 | 4 | Rat | 8.2 | pIC50 | = | 8.2 | Functional | Drug Central | None | None | None | None | None | ||||
91933454 | 3781 | 13 | None | -34 | 4 | Rat | 8.2 | pIC50 | = | 8.2 | Functional | Drug Central | None | None | None | None | None | ||||
CHEMBL525610 | 3781 | 13 | None | -34 | 4 | Rat | 8.2 | pIC50 | = | 8.2 | Functional | Drug Central | None | None | None | None | None | ||||
DB06285 | 3781 | 13 | None | -34 | 4 | Rat | 8.2 | pIC50 | = | 8.2 | Functional | Drug Central | None | None | None | None | None | ||||
129631922 | 3781 | 13 | None | -7 | 4 | Human | 8.1 | pIC50 | = | 8.1 | Functional | Drug Central | None | None | None | None | None | ||||
132274287 | 3781 | 13 | None | -7 | 4 | Human | 8.1 | pIC50 | = | 8.1 | Functional | Drug Central | None | None | None | None | None | ||||
132451761 | 3781 | 13 | None | -7 | 4 | Human | 8.1 | pIC50 | = | 8.1 | Functional | Drug Central | None | None | None | None | None | ||||
155817470 | 3781 | 13 | None | -7 | 4 | Human | 8.1 | pIC50 | = | 8.1 | Functional | Drug Central | None | None | None | None | None | ||||
16132393 | 3781 | 13 | None | -7 | 4 | Human | 8.1 | pIC50 | = | 8.1 | Functional | Drug Central | None | None | None | None | None | ||||
16133850 | 3781 | 13 | None | -7 | 4 | Human | 8.1 | pIC50 | = | 8.1 | Functional | Drug Central | None | None | None | None | None | ||||
4448 | 3781 | 13 | None | -7 | 4 | Human | 8.1 | pIC50 | = | 8.1 | Functional | Drug Central | None | None | None | None | None | ||||
4514 | 3781 | 13 | None | -7 | 4 | Human | 8.1 | pIC50 | = | 8.1 | Functional | Drug Central | None | None | None | None | None | ||||
91933454 | 3781 | 13 | None | -7 | 4 | Human | 8.1 | pIC50 | = | 8.1 | Functional | Drug Central | None | None | None | None | None | ||||
CHEMBL525610 | 3781 | 13 | None | -7 | 4 | Human | 8.1 | pIC50 | = | 8.1 | Functional | Drug Central | None | None | None | None | None | ||||
DB06285 | 3781 | 13 | None | -7 | 4 | Human | 8.1 | pIC50 | = | 8.1 | Functional | Drug Central | None | None | None | None | None | ||||
155817427 | 3232 | 0 | None | -158 | 3 | Rat | 5.5 | pIC50 | = | 5.5 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
1788 | 3232 | 0 | None | -158 | 3 | Rat | 5.5 | pIC50 | = | 5.5 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
129316189 | 3229 | 0 | None | -35 | 3 | Rat | 6.8 | pIC50 | = | 6.8 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
155817471 | 3229 | 0 | None | -35 | 3 | Rat | 6.8 | pIC50 | = | 6.8 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
16201228 | 3229 | 0 | None | -35 | 3 | Rat | 6.8 | pIC50 | = | 6.8 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
4449 | 3229 | 0 | None | -35 | 3 | Rat | 6.8 | pIC50 | = | 6.8 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
1824 | 2003 | 0 | None | - | 1 | Human | 7.0 | pIC50 | = | 7 | Functional | Guide to Pharmacology | None | None | None | None | 10537121 | ||||
155817427 | 3232 | 0 | None | -1 | 3 | Human | 7.5 | pIC50 | = | 7.5 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
155817427 | 3232 | 0 | None | -1 | 3 | Human | 7.5 | pIC50 | = | 7.5 | Functional | Guide to Pharmacology | None | None | None | None | 8702701 | ||||
1788 | 3232 | 0 | None | -1 | 3 | Human | 7.5 | pIC50 | = | 7.5 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
1788 | 3232 | 0 | None | -1 | 3 | Human | 7.5 | pIC50 | = | 7.5 | Functional | Guide to Pharmacology | None | None | None | None | 8702701 | ||||
129631922 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
129631922 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 8702701 | ||||
132274287 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
132274287 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 8702701 | ||||
132451761 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
132451761 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 8702701 | ||||
155817470 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
155817470 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 8702701 | ||||
16132393 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
16132393 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 8702701 | ||||
16133850 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
16133850 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 8702701 | ||||
4448 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
4448 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 8702701 | ||||
4514 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
4514 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 8702701 | ||||
91933454 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
91933454 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 8702701 | ||||
CHEMBL525610 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
CHEMBL525610 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 8702701 | ||||
DB06285 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
DB06285 | 3781 | 13 | None | -7 | 4 | Human | 7.8 | pIC50 | = | 7.8 | Functional | Guide to Pharmacology | None | None | None | None | 8702701 | ||||
3624 | 3826 | 0 | None | -5 | 2 | Rat | 8.1 | pIC50 | = | 8.1 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
1815 | 3825 | 0 | None | 25 | 3 | Human | 8.4 | pIC50 | = | 8.4 | Functional | Guide to Pharmacology | None | None | None | None | 10854439 | ||||
1815 | 3825 | 0 | None | 25 | 3 | Human | 8.4 | pIC50 | = | 8.4 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
3624 | 3826 | 0 | None | 5 | 2 | Human | 8.8 | pIC50 | = | 8.8 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
155817432 | 3233 | 0 | None | -446 | 3 | Rat | 5.3 | pIC50 | None | 5.3 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
16144017 | 3233 | 0 | None | -446 | 3 | Rat | 5.3 | pIC50 | None | 5.3 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
1822 | 3233 | 0 | None | -446 | 3 | Rat | 5.3 | pIC50 | None | 5.3 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
155817428 | 3234 | 0 | None | -6 | 2 | Human | 5.7 | pIC50 | None | 5.7 | Functional | Guide to Pharmacology | None | None | None | None | 8702701 | ||||
1790 | 3234 | 0 | None | -6 | 2 | Human | 5.7 | pIC50 | None | 5.7 | Functional | Guide to Pharmacology | None | None | None | None | 8702701 | ||||
155817432 | 3233 | 0 | None | -70 | 3 | Human | 6.1 | pIC50 | None | 6.1 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
16144017 | 3233 | 0 | None | -70 | 3 | Human | 6.1 | pIC50 | None | 6.1 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
1822 | 3233 | 0 | None | -70 | 3 | Human | 6.1 | pIC50 | None | 6.1 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
155817433 | 3828 | 0 | None | -125 | 3 | Rat | 6.1 | pIC50 | None | 6.1 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
16134968 | 3828 | 0 | None | -125 | 3 | Rat | 6.1 | pIC50 | None | 6.1 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
1827 | 3828 | 0 | None | -125 | 3 | Rat | 6.1 | pIC50 | None | 6.1 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
1825 | 1996 | 0 | None | - | 1 | Human | 6.2 | pIC50 | None | 6.2 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
1820 | 1497 | 0 | None | -10 | 2 | Rat | 6.3 | pIC50 | None | 6.3 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
1807 | 3104 | 0 | None | -5 | 2 | Human | 6.3 | pIC50 | None | 6.3 | Functional | Guide to Pharmacology | None | None | None | None | 8702701 | ||||
129631922 | 3781 | 13 | None | -34 | 4 | Rat | 6.3 | pIC50 | None | 6.3 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
132274287 | 3781 | 13 | None | -34 | 4 | Rat | 6.3 | pIC50 | None | 6.3 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
132451761 | 3781 | 13 | None | -34 | 4 | Rat | 6.3 | pIC50 | None | 6.3 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
155817470 | 3781 | 13 | None | -34 | 4 | Rat | 6.3 | pIC50 | None | 6.3 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
16132393 | 3781 | 13 | None | -34 | 4 | Rat | 6.3 | pIC50 | None | 6.3 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
16133850 | 3781 | 13 | None | -34 | 4 | Rat | 6.3 | pIC50 | None | 6.3 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
4448 | 3781 | 13 | None | -34 | 4 | Rat | 6.3 | pIC50 | None | 6.3 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
4514 | 3781 | 13 | None | -34 | 4 | Rat | 6.3 | pIC50 | None | 6.3 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
91933454 | 3781 | 13 | None | -34 | 4 | Rat | 6.3 | pIC50 | None | 6.3 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
CHEMBL525610 | 3781 | 13 | None | -34 | 4 | Rat | 6.3 | pIC50 | None | 6.3 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
DB06285 | 3781 | 13 | None | -34 | 4 | Rat | 6.3 | pIC50 | None | 6.3 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
155817434 | 3829 | 0 | None | -50 | 2 | Rat | 6.5 | pIC50 | None | 6.5 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
1828 | 3829 | 0 | None | -50 | 2 | Rat | 6.5 | pIC50 | None | 6.5 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
1794 | 1930 | 0 | None | 19 | 3 | Human | 6.6 | pIC50 | None | 6.6 | Functional | Guide to Pharmacology | None | None | None | None | 8702701 | ||||
155817429 | 3235 | 0 | None | -3 | 2 | Human | 6.7 | pIC50 | None | 6.7 | Functional | Guide to Pharmacology | None | None | None | None | 11046116 | ||||
1814 | 3235 | 0 | None | -3 | 2 | Human | 6.7 | pIC50 | None | 6.7 | Functional | Guide to Pharmacology | None | None | None | None | 11046116 | ||||
1801 | 2001 | 0 | None | -3 | 2 | Human | 6.8 | pIC50 | None | 6.8 | Functional | Guide to Pharmacology | None | None | None | None | 10537121 | ||||
1819 | 1498 | 0 | None | -3 | 2 | Human | 6.9 | pIC50 | None | 6.9 | Functional | Guide to Pharmacology | None | None | None | None | 11046116 | ||||
1821 | 2002 | 0 | None | -1 | 2 | Human | 7.0 | pIC50 | None | 7 | Functional | Guide to Pharmacology | None | None | None | None | 10537121 | ||||
1815 | 3825 | 0 | None | -25 | 3 | Rat | 7.0 | pIC50 | None | 7 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
155817433 | 3828 | 0 | None | -12 | 3 | Human | 7.1 | pIC50 | None | 7.1 | Functional | Guide to Pharmacology | None | None | None | None | 11046116 | ||||
155817433 | 3828 | 0 | None | -12 | 3 | Human | 7.1 | pIC50 | None | 7.1 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
16134968 | 3828 | 0 | None | -12 | 3 | Human | 7.1 | pIC50 | None | 7.1 | Functional | Guide to Pharmacology | None | None | None | None | 11046116 | ||||
16134968 | 3828 | 0 | None | -12 | 3 | Human | 7.1 | pIC50 | None | 7.1 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
1827 | 3828 | 0 | None | -12 | 3 | Human | 7.1 | pIC50 | None | 7.1 | Functional | Guide to Pharmacology | None | None | None | None | 11046116 | ||||
1827 | 3828 | 0 | None | -12 | 3 | Human | 7.1 | pIC50 | None | 7.1 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
1800 | 2000 | 0 | None | -3 | 2 | Human | 7.2 | pIC50 | None | 7.2 | Functional | Guide to Pharmacology | None | None | None | None | 10537121 | ||||
1820 | 1497 | 0 | None | 10 | 2 | Human | 7.3 | pIC50 | None | 7.3 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
1799 | 1999 | 0 | None | -1 | 2 | Human | 7.3 | pIC50 | None | 7.3 | Functional | Guide to Pharmacology | None | None | None | None | 10537121 | ||||
1808 | 3872 | 0 | None | 2 | 2 | Human | 7.4 | pIC50 | None | 7.4 | Functional | Guide to Pharmacology | None | None | None | None | 9360953 | ||||
1809 | 3871 | 0 | None | 1 | 2 | Human | 7.5 | pIC50 | None | 7.5 | Functional | Guide to Pharmacology | None | None | None | None | 8702701 | ||||
1798 | 1998 | 0 | None | -1 | 2 | Human | 7.6 | pIC50 | None | 7.6 | Functional | Guide to Pharmacology | None | None | None | None | 10537121 | ||||
1798 | 1998 | 0 | None | -1 | 2 | Human | 7.6 | pIC50 | None | 7.6 | Functional | Guide to Pharmacology | None | None | None | None | 8702701 | ||||
1797 | 2004 | 0 | None | 1 | 2 | Human | 7.7 | pIC50 | None | 7.7 | Functional | Guide to Pharmacology | None | None | None | None | 9360953 | ||||
155817434 | 3829 | 0 | None | 50 | 2 | Human | 8.2 | pIC50 | None | 8.2 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
1828 | 3829 | 0 | None | 50 | 2 | Human | 8.2 | pIC50 | None | 8.2 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
129316189 | 3229 | 0 | None | 15 | 3 | Human | 8.4 | pIC50 | None | 8.4 | Functional | Guide to Pharmacology | None | None | None | None | 10537121 | ||||
129316189 | 3229 | 0 | None | 15 | 3 | Human | 8.4 | pIC50 | None | 8.4 | Functional | Guide to Pharmacology | None | None | None | None | 10854439 | ||||
129316189 | 3229 | 0 | None | 15 | 3 | Human | 8.4 | pIC50 | None | 8.4 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
155817471 | 3229 | 0 | None | 15 | 3 | Human | 8.4 | pIC50 | None | 8.4 | Functional | Guide to Pharmacology | None | None | None | None | 10537121 | ||||
155817471 | 3229 | 0 | None | 15 | 3 | Human | 8.4 | pIC50 | None | 8.4 | Functional | Guide to Pharmacology | None | None | None | None | 10854439 | ||||
155817471 | 3229 | 0 | None | 15 | 3 | Human | 8.4 | pIC50 | None | 8.4 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
16201228 | 3229 | 0 | None | 15 | 3 | Human | 8.4 | pIC50 | None | 8.4 | Functional | Guide to Pharmacology | None | None | None | None | 10537121 | ||||
16201228 | 3229 | 0 | None | 15 | 3 | Human | 8.4 | pIC50 | None | 8.4 | Functional | Guide to Pharmacology | None | None | None | None | 10854439 | ||||
16201228 | 3229 | 0 | None | 15 | 3 | Human | 8.4 | pIC50 | None | 8.4 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 | ||||
4449 | 3229 | 0 | None | 15 | 3 | Human | 8.4 | pIC50 | None | 8.4 | Functional | Guide to Pharmacology | None | None | None | None | 10537121 | ||||
4449 | 3229 | 0 | None | 15 | 3 | Human | 8.4 | pIC50 | None | 8.4 | Functional | Guide to Pharmacology | None | None | None | None | 10854439 | ||||
4449 | 3229 | 0 | None | 15 | 3 | Human | 8.4 | pIC50 | None | 8.4 | Functional | Guide to Pharmacology | None | None | None | None | 11602681 |
Ligands (move mouse cursor over ligand name to see structure) | Receptor | Assay information | Chemical information | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Similar- ity |
Common name |
GPCRdb ID |
#Vendors |
Reference ligand |
Fold selectivity |
# Tested GPCRs |
Species |
p-value (-log) |
Activity Type |
Activity Relation |
Activity Value |
Assay Type |
Assay Description |
Source |
Mol weight |
Rot Bonds |
H don |
H acc |
LogP |
Smiles |
DOI |