CaS receptor

GPCR CLASS (FAMILY)

Class C (Glutamate)

PDB CODE

8SZF

SPECIES

Homo sapiens

RESOLUTION

2.8 Å

PREFERRED CHAIN

A

REFERENCE

10.1038/S41586-024-07055-2

PUBLICATION DATE

Feb. 7, 2024

3D VIEW

NGL is a WebGL based 3D viewer powered by MMTF.

LIGAND INTERACTIONS

72 interactions (Click to see)

LIGANDS

spermine - Agonist pubchem gtoplig chembl_ligand drugbank ,

cinacalcet - PAM pubchem gtoplig chembl_ligand drugbank drug_central ,

Calcium - Agonist pubchem ,

Calcium - Agonist pubchem ,

D-tryptophan - Co-agonist pubchem gtoplig chembl_ligand drugbank pubchem gtoplig chembl_ligand drugbank drug_central

PHYSIOLOGICAL LIGANDS

D-tryptophan, Mg2+, spermine, Ca2+