CXCR4

GPCR CLASS (FAMILY)

Class A (Rhodopsin)

PDB CODE

8U4S

SPECIES

Homo sapiens

RESOLUTION

3.4 Å

PREFERRED CHAIN

C

REFERENCE

10.1038/S41594-024-01397-1

PUBLICATION DATE

March 13, 2024

3D VIEW

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LIGAND INTERACTIONS

65 interactions (Click to see)

LIGANDS

REGN7663 Fab (chain A) - Inverse agonist ,

REGN7663 Fab (chain B) - Inverse agonist

PHYSIOLOGICAL LIGANDS

CXCL12ε (Human), CXCL12 (Mouse), CXCL12δ (Human), CXCL12α (Human), CXCL12β (Human), CXCL12φ (Human), CXCL12γ (Human)