( Vismodegib - SMO model)

GPCR CLASS (FAMILY)

F (Frizzled)

SPECIES

Homo sapiens

LIGAND

Vismodegib

DATE

2026-03-01

ORIGIN

Model (Boltz2)

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Tertiary structure confidence

pLDDT score avg.: 69.0

Very high (>90)
Confident (90-70)
Low (70-50)
Very low (<50)
Disordered

PTM Score: 0.8
iPTM Score: 1.0
Ligand pLDDT Score: 0.3
Vicinity pLDDT (5Å): 0.9
Ligand iPTM Score: 1.0