Biased Signaling Atlas

Refined structure (7V9M) of G_s - GHRH receptor

Full

GPCR CLASS (FAMILY)

B1 (Secretin)

SPECIES

Homo sapiens

G PROTEIN FAMILY

G_s

DATE

2024-02-01

3D VIEW

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Structure

GPCR

Gα

Gβ

Gγ
Model

AlphaFold2-Multimer

REFINED G PROTEIN RESIDUES

Residue backbones - 224 from structure (56.9%), 170 from model (43.1%)
Residue sidechains - 216 from structure (54.8%), 178 from model (45.2%)

Showing 1 to 394 of 394 entries

Search:

Segment	Seq.num.	AA	CGN#	Backbone from	Sidechain from
	:

Segment	Seq.num.	AA	CGN#	Backbone from	Sidechain from

G.HN	1	M	G.HN.01	AF2	AF2
G.HN	2	G	G.HN.02	AF2	AF2
G.HN	3	C	G.HN.09	AF2	AF2
G.HN	4	L	G.HN.10	AF2	AF2
G.HN	5	G	G.HN.11	AF2	AF2
G.HN	6	N	G.HN.22	AF2	AF2
G.HN	7	S	G.HN.23	AF2	AF2
G.HN	8	K	G.HN.24	AF2	AF2
G.HN	9	T	G.HN.26	AF2	AF2
G.HN	10	E	G.HN.27	Structure	Structure
G.HN	11	D	G.HN.28	Structure	Structure
G.HN	12	Q	G.HN.29	Structure	Structure
G.HN	13	R	G.HN.30	Structure	Structure
G.HN	14	N	G.HN.31	Structure	Structure
G.HN	15	E	G.HN.32	Structure	Structure
G.HN	16	E	G.HN.33	Structure	Structure
G.HN	17	K	G.HN.34	Structure	Structure
G.HN	18	A	G.HN.35	Structure	Structure
G.HN	19	Q	G.HN.36	Structure	Structure
G.HN	20	R	G.HN.37	Structure	Structure
G.HN	21	E	G.HN.38	Structure	Structure
G.HN	22	A	G.HN.39	Structure	Structure
G.HN	23	N	G.HN.40	Structure	Structure
G.HN	24	K	G.HN.41	Structure	Structure
G.HN	25	K	G.HN.42	Structure	Structure
G.HN	26	I	G.HN.43	Structure	Structure
G.HN	27	E	G.HN.44	Structure	Structure
G.HN	28	K	G.HN.45	Structure	Structure
G.HN	29	Q	G.HN.46	Structure	Structure
G.HN	30	L	G.HN.47	Structure	Structure
G.HN	31	Q	G.HN.48	Structure	Structure
G.HN	32	K	G.HN.49	Structure	Structure
G.HN	33	D	G.HN.50	Structure	Structure
G.HN	34	K	G.HN.51	Structure	Structure
G.HN	35	Q	G.HN.52	Structure	Structure
G.HN	36	V	G.HN.53	Structure	Structure
G.hns1	37	Y	G.hns1.01	Structure	Structure
G.hns1	38	R	G.hns1.02	Structure	Structure
G.hns1	39	A	G.hns1.03	Structure	Structure
G.S1	40	T	G.S1.01	Structure	Structure
G.S1	41	H	G.S1.02	Structure	Structure
G.S1	42	R	G.S1.03	Structure	Structure
G.S1	43	L	G.S1.04	Structure	Structure
G.S1	44	L	G.S1.05	Structure	Structure
G.S1	45	L	G.S1.06	Structure	Structure
G.S1	46	L	G.S1.07	Structure	Structure
G.s1h1	47	G	G.s1h1.01	Structure	Structure
G.s1h1	48	A	G.s1h1.02	Structure	Structure
G.s1h1	49	G	G.s1h1.03	AF2	AF2
G.s1h1	50	E	G.s1h1.04	AF2	AF2
G.s1h1	51	S	G.s1h1.05	AF2	AF2
G.s1h1	52	G	G.s1h1.06	Structure	Structure
G.H1	53	K	G.H1.01	Structure	Structure
G.H1	54	S	G.H1.02	Structure	AF2
G.H1	55	T	G.H1.03	Structure	Structure
G.H1	56	I	G.H1.04	Structure	Structure
G.H1	57	V	G.H1.05	Structure	Structure
G.H1	58	K	G.H1.06	Structure	Structure
G.H1	59	Q	G.H1.07	Structure	Structure
G.H1	60	M	G.H1.08	Structure	Structure
G.H1	61	R	G.H1.09	AF2	AF2
G.H1	62	I	G.H1.10	AF2	AF2
G.H1	63	L	G.H1.11	AF2	AF2
G.H1	64	H	G.H1.12	AF2	AF2
G.h1ha	65	V	G.h1ha.01	AF2	AF2
G.h1ha	66	N	G.h1ha.02	AF2	AF2
G.h1ha	67	G	G.h1ha.03	AF2	AF2
G.h1ha	68	F	G.h1ha.04	AF2	AF2
G.h1ha	69	N	G.h1ha.05	AF2	AF2
G.h1ha	70	G	G.h1ha.06	AF2	AF2
G.h1ha	71	E	G.h1ha.07	AF2	AF2
G.h1ha	72	G	G.h1ha.08	AF2	AF2
G.h1ha	73	G	G.h1ha.09	AF2	AF2
G.h1ha	74	E	G.h1ha.10	AF2	AF2
G.h1ha	75	E	G.h1ha.11	AF2	AF2
G.h1ha	76	D	G.h1ha.12	AF2	AF2
G.h1ha	77	P	G.h1ha.13	AF2	AF2
G.h1ha	78	Q	G.h1ha.14	AF2	AF2
G.h1ha	79	A	G.h1ha.15	AF2	AF2
G.h1ha	80	A	G.h1ha.16	AF2	AF2
G.h1ha	81	R	G.h1ha.17	AF2	AF2
G.h1ha	82	S	G.h1ha.18	AF2	AF2
G.h1ha	83	N	G.h1ha.19	AF2	AF2
G.h1ha	84	S	G.h1ha.20	AF2	AF2
H.HA	85	D	H.HA.01	AF2	AF2
H.HA	86	G	H.HA.02	AF2	AF2
H.HA	87	E	H.HA.03	AF2	AF2
H.HA	88	K	H.HA.04	AF2	AF2
H.HA	89	A	H.HA.05	AF2	AF2
H.HA	90	T	H.HA.06	AF2	AF2
H.HA	91	K	H.HA.07	AF2	AF2
H.HA	92	V	H.HA.08	AF2	AF2
H.HA	93	Q	H.HA.09	AF2	AF2
H.HA	94	D	H.HA.10	AF2	AF2
H.HA	95	I	H.HA.11	AF2	AF2
H.HA	96	K	H.HA.12	AF2	AF2
H.HA	97	N	H.HA.13	AF2	AF2
H.HA	98	N	H.HA.14	AF2	AF2
H.HA	99	L	H.HA.15	AF2	AF2
H.HA	100	K	H.HA.16	AF2	AF2
H.HA	101	E	H.HA.17	AF2	AF2
H.HA	102	A	H.HA.18	AF2	AF2
H.HA	103	I	H.HA.19	AF2	AF2
H.HA	104	E	H.HA.20	AF2	AF2
H.HA	105	T	H.HA.21	AF2	AF2
H.HA	106	I	H.HA.22	AF2	AF2
H.HA	107	V	H.HA.23	AF2	AF2
H.HA	108	A	H.HA.24	AF2	AF2
H.HA	109	A	H.HA.25	AF2	AF2
H.HA	110	M	H.HA.26	AF2	AF2
H.HA	111	S	H.HA.27	AF2	AF2
H.HA	112	N	H.HA.28	AF2	AF2
H.HA	113	L	H.HA.29	AF2	AF2
H.hahb	114	V	H.hahb.01	AF2	AF2
H.hahb	115	P	H.hahb.02	AF2	AF2
H.hahb	116	P	H.hahb.03	AF2	AF2
H.hahb	117	V	H.hahb.04	AF2	AF2
H.hahb	118	E	H.hahb.05	AF2	AF2
H.hahb	119	L	H.hahb.06	AF2	AF2
H.hahb	120	A	H.hahb.07	AF2	AF2
H.hahb	121	N	H.hahb.08	AF2	AF2
H.hahb	122	P	H.hahb.09	AF2	AF2
H.HB	123	E	H.HB.01	AF2	AF2
H.HB	124	N	H.HB.02	AF2	AF2
H.HB	125	Q	H.HB.03	AF2	AF2
H.HB	126	F	H.HB.04	AF2	AF2
H.HB	127	R	H.HB.05	AF2	AF2
H.HB	128	V	H.HB.06	AF2	AF2
H.HB	129	D	H.HB.07	AF2	AF2
H.HB	130	Y	H.HB.08	AF2	AF2
H.HB	131	I	H.HB.09	AF2	AF2
H.HB	132	L	H.HB.10	AF2	AF2
H.HB	133	S	H.HB.11	AF2	AF2
H.HB	134	V	H.HB.12	AF2	AF2
H.HB	135	M	H.HB.13	AF2	AF2
H.HB	136	N	H.HB.14	AF2	AF2
H.hbhc	137	V	H.hbhc.01	AF2	AF2
H.hbhc	138	P	H.hbhc.02	AF2	AF2
H.hbhc	139	D	H.hbhc.03	AF2	AF2
H.hbhc	140	F	H.hbhc.04	AF2	AF2
H.hbhc	141	D	H.hbhc.13	AF2	AF2
H.hbhc	142	F	H.hbhc.14	AF2	AF2
H.hbhc	143	P	H.hbhc.15	AF2	AF2
H.HC	144	P	H.HC.01	AF2	AF2
H.HC	145	E	H.HC.02	AF2	AF2
H.HC	146	F	H.HC.03	AF2	AF2
H.HC	147	Y	H.HC.04	AF2	AF2
H.HC	148	E	H.HC.05	AF2	AF2
H.HC	149	H	H.HC.06	AF2	AF2
H.HC	150	A	H.HC.07	AF2	AF2
H.HC	151	K	H.HC.08	AF2	AF2
H.HC	152	A	H.HC.09	AF2	AF2
H.HC	153	L	H.HC.10	AF2	AF2
H.HC	154	W	H.HC.11	AF2	AF2
H.HC	155	E	H.HC.12	AF2	AF2
H.hchd	156	D	H.hchd.01	AF2	AF2
H.HD	157	E	H.HD.01	AF2	AF2
H.HD	158	G	H.HD.02	AF2	AF2
H.HD	159	V	H.HD.03	AF2	AF2
H.HD	160	R	H.HD.04	AF2	AF2
H.HD	161	A	H.HD.05	AF2	AF2
H.HD	162	C	H.HD.06	AF2	AF2
H.HD	163	Y	H.HD.07	AF2	AF2
H.HD	164	E	H.HD.08	AF2	AF2
H.HD	165	R	H.HD.09	AF2	AF2
H.HD	166	S	H.HD.10	AF2	AF2
H.HD	167	N	H.HD.11	AF2	AF2
H.HD	168	E	H.HD.12	AF2	AF2
H.hdhe	169	Y	H.hdhe.01	AF2	AF2
H.hdhe	170	Q	H.hdhe.02	AF2	AF2
H.hdhe	171	L	H.hdhe.03	AF2	AF2
H.hdhe	172	I	H.hdhe.04	AF2	AF2
H.hdhe	173	D	H.hdhe.05	AF2	AF2
H.HE	174	C	H.HE.01	AF2	AF2
H.HE	175	A	H.HE.02	AF2	AF2
H.HE	176	Q	H.HE.03	AF2	AF2
H.HE	177	Y	H.HE.04	AF2	AF2
H.HE	178	F	H.HE.05	AF2	AF2
H.HE	179	L	H.HE.06	AF2	AF2
H.HE	180	D	H.HE.07	AF2	AF2
H.HE	181	K	H.HE.08	AF2	AF2
H.HE	182	I	H.HE.09	AF2	AF2
H.HE	183	D	H.HE.10	AF2	AF2
H.HE	184	V	H.HE.11	AF2	AF2
H.HE	185	I	H.HE.12	AF2	AF2
H.HE	186	K	H.HE.13	AF2	AF2
H.hehf	187	Q	H.hehf.01	AF2	AF2
H.hehf	188	A	H.hehf.02	AF2	AF2
H.hehf	189	D	H.hehf.03	AF2	AF2
H.hehf	190	Y	H.hehf.04	AF2	AF2
H.hehf	191	V	H.hehf.05	AF2	AF2
H.hehf	192	P	H.hehf.06	AF2	AF2
H.hehf	193	S	H.hehf.07	AF2	AF2
H.HF	194	D	H.HF.01	AF2	AF2
H.HF	195	Q	H.HF.02	AF2	AF2
H.HF	196	D	H.HF.03	AF2	AF2
H.HF	197	L	H.HF.04	AF2	AF2
H.HF	198	L	H.HF.05	AF2	AF2
H.HF	199	R	H.HF.06	AF2	AF2
G.hfs2	200	C	G.hfs2.01	AF2	AF2
G.hfs2	201	R	G.hfs2.02	AF2	AF2
G.hfs2	202	V	G.hfs2.03	AF2	AF2
G.hfs2	203	L	G.hfs2.04	AF2	AF2
G.hfs2	204	T	G.hfs2.05	AF2	AF2
G.hfs2	205	S	G.hfs2.06	Structure	Structure
G.hfs2	206	G	G.hfs2.07	Structure	Structure
G.S2	207	I	G.S2.01	Structure	Structure
G.S2	208	F	G.S2.02	Structure	Structure
G.S2	209	E	G.S2.03	Structure	Structure
G.S2	210	T	G.S2.04	Structure	Structure
G.S2	211	K	G.S2.05	Structure	Structure
G.S2	212	F	G.S2.06	Structure	Structure
G.S2	213	Q	G.S2.07	Structure	Structure
G.S2	214	V	G.S2.08	Structure	Structure
G.s2s3	215	D	G.s2s3.01	Structure	Structure
G.s2s3	216	K	G.s2s3.02	Structure	Structure
G.S3	217	V	G.S3.01	Structure	Structure
G.S3	218	N	G.S3.02	Structure	Structure
G.S3	219	F	G.S3.03	Structure	Structure
G.S3	220	H	G.S3.04	Structure	Structure
G.S3	221	M	G.S3.05	Structure	Structure
G.S3	222	F	G.S3.06	Structure	Structure
G.S3	223	D	G.S3.07	Structure	Structure
G.S3	224	V	G.S3.08	Structure	Structure
G.s3h2	225	G	G.s3h2.01	Structure	Structure
G.s3h2	226	G	G.s3h2.02	Structure	AF2
G.s3h2	227	Q	G.s3h2.03	Structure	Structure
G.H2	228	R	G.H2.01	Structure	Structure
G.H2	229	D	G.H2.02	Structure	Structure
G.H2	230	E	G.H2.03	Structure	Structure
G.H2	231	R	G.H2.04	Structure	Structure
G.H2	232	R	G.H2.05	Structure	Structure
G.H2	233	K	G.H2.06	Structure	Structure
G.H2	234	W	G.H2.07	Structure	Structure
G.H2	235	I	G.H2.08	Structure	Structure
G.H2	236	Q	G.H2.09	Structure	Structure
G.H2	237	C	G.H2.10	Structure	Structure
G.h2s4	238	F	G.h2s4.01	Structure	Structure
G.h2s4	239	N	G.h2s4.02	Structure	Structure
G.h2s4	240	D	G.h2s4.03	Structure	Structure
G.h2s4	241	V	G.h2s4.04	Structure	Structure
G.h2s4	242	T	G.h2s4.05	Structure	Structure
G.S4	243	A	G.S4.01	Structure	Structure
G.S4	244	I	G.S4.02	Structure	Structure
G.S4	245	I	G.S4.03	Structure	Structure
G.S4	246	F	G.S4.04	Structure	Structure
G.S4	247	V	G.S4.05	Structure	Structure
G.S4	248	V	G.S4.06	Structure	Structure
G.S4	249	A	G.S4.07	Structure	Structure
G.s4h3	250	S	G.s4h3.01	Structure	Structure
G.s4h3	251	S	G.s4h3.02	Structure	Structure
G.s4h3	252	S	G.s4h3.03	AF2	AF2
G.s4h3	253	Y	G.s4h3.04	AF2	AF2
G.s4h3	254	N	G.s4h3.05	AF2	AF2
G.s4h3	255	M	G.s4h3.06	AF2	AF2
G.s4h3	256	V	G.s4h3.07	AF2	AF2
G.s4h3	257	I	G.s4h3.08	AF2	AF2
G.s4h3	258	R	G.s4h3.09	AF2	AF2
G.s4h3	259	E	G.s4h3.10	AF2	AF2
G.s4h3	260	D	G.s4h3.11	AF2	AF2
G.s4h3	261	N	G.s4h3.12	AF2	AF2
G.s4h3	262	Q	G.s4h3.13	AF2	AF2
G.s4h3	263	T	G.s4h3.14	Structure	Structure
G.s4h3	264	N	G.s4h3.15	Structure	Structure
G.H3	265	R	G.H3.01	Structure	Structure
G.H3	266	L	G.H3.02	Structure	Structure
G.H3	267	Q	G.H3.03	Structure	Structure
G.H3	268	E	G.H3.04	Structure	AF2
G.H3	269	A	G.H3.05	Structure	Structure
G.H3	270	L	G.H3.06	Structure	Structure
G.H3	271	N	G.H3.07	Structure	AF2
G.H3	272	L	G.H3.08	Structure	Structure
G.H3	273	F	G.H3.09	Structure	Structure
G.H3	274	K	G.H3.10	Structure	AF2
G.H3	275	S	G.H3.11	Structure	Structure
G.H3	276	I	G.H3.12	Structure	Structure
G.H3	277	W	G.H3.13	Structure	Structure
G.H3	278	N	G.H3.14	Structure	Structure
G.H3	279	N	G.H3.15	Structure	Structure
G.H3	280	R	G.H3.16	Structure	AF2
G.H3	281	W	G.H3.17	Structure	Structure
G.H3	282	L	G.H3.18	Structure	Structure
G.h3s5	283	R	G.h3s5.01	Structure	Structure
G.h3s5	284	T	G.h3s5.02	Structure	AF2
G.h3s5	285	I	G.h3s5.03	Structure	AF2
G.S5	286	S	G.S5.01	Structure	Structure
G.S5	287	V	G.S5.02	Structure	Structure
G.S5	288	I	G.S5.03	Structure	Structure
G.S5	289	L	G.S5.04	Structure	Structure
G.S5	290	F	G.S5.05	Structure	Structure
G.S5	291	L	G.S5.06	Structure	Structure
G.S5	292	N	G.S5.07	Structure	Structure
G.s5hg	293	K	G.s5hg.01	Structure	Structure
G.HG	294	Q	G.HG.01	Structure	Structure
G.HG	295	D	G.HG.02	Structure	Structure
G.HG	296	L	G.HG.03	Structure	Structure
G.HG	297	L	G.HG.04	Structure	Structure
G.HG	298	A	G.HG.05	Structure	Structure
G.HG	299	E	G.HG.06	Structure	Structure
G.HG	300	K	G.HG.07	Structure	Structure
G.HG	301	V	G.HG.08	Structure	Structure
G.HG	302	L	G.HG.09	Structure	Structure
G.HG	303	A	G.HG.10	Structure	Structure
G.HG	304	G	G.HG.11	AF2	AF2
G.HG	305	K	G.HG.12	AF2	AF2
G.HG	306	S	G.HG.13	AF2	AF2
G.HG	307	K	G.HG.14	Structure	Structure
G.HG	308	I	G.HG.15	Structure	Structure
G.HG	309	E	G.HG.16	Structure	Structure
G.HG	310	D	G.HG.17	Structure	Structure
G.hgh4	311	Y	G.hgh4.01	Structure	Structure
G.hgh4	312	F	G.hgh4.02	Structure	Structure
G.hgh4	313	P	G.hgh4.03	Structure	Structure
G.hgh4	314	E	G.hgh4.04	Structure	Structure
G.hgh4	315	F	G.hgh4.05	Structure	Structure
G.hgh4	316	A	G.hgh4.06	Structure	Structure
G.hgh4	317	R	G.hgh4.07	Structure	Structure
G.hgh4	318	Y	G.hgh4.08	Structure	Structure
G.hgh4	319	T	G.hgh4.09	Structure	Structure
G.hgh4	320	T	G.hgh4.10	Structure	Structure
G.hgh4	321	P	G.hgh4.11	Structure	Structure
G.hgh4	322	E	G.hgh4.12	Structure	Structure
G.hgh4	323	D	G.hgh4.13	Structure	Structure
G.hgh4	324	A	G.hgh4.14	Structure	Structure
G.hgh4	325	T	G.hgh4.15	Structure	Structure
G.hgh4	326	P	G.hgh4.16	Structure	Structure
G.hgh4	327	E	G.hgh4.17	Structure	Structure
G.hgh4	328	P	G.hgh4.18	Structure	Structure
G.hgh4	329	G	G.hgh4.19	Structure	Structure
G.hgh4	330	E	G.hgh4.20	Structure	Structure
G.hgh4	331	D	G.hgh4.21	Structure	Structure
G.H4	332	P	G.H4.01	Structure	Structure
G.H4	333	R	G.H4.02	Structure	Structure
G.H4	334	V	G.H4.03	Structure	Structure
G.H4	335	T	G.H4.04	Structure	Structure
G.H4	336	R	G.H4.05	Structure	Structure
G.H4	337	A	G.H4.06	Structure	Structure
G.H4	338	K	G.H4.07	Structure	Structure
G.H4	339	Y	G.H4.08	Structure	Structure
G.H4	340	F	G.H4.10	Structure	Structure
G.H4	341	I	G.H4.11	Structure	Structure
G.H4	342	R	G.H4.12	Structure	Structure
G.H4	343	D	G.H4.13	Structure	Structure
G.H4	344	E	G.H4.14	Structure	Structure
G.H4	345	F	G.H4.15	Structure	Structure
G.H4	346	L	G.H4.16	Structure	Structure
G.H4	347	R	G.H4.17	Structure	Structure
G.h4s6	348	I	G.h4s6.01	Structure	Structure
G.h4s6	349	S	G.h4s6.02	Structure	Structure
G.h4s6	350	T	G.h4s6.03	Structure	Structure
G.h4s6	351	A	G.h4s6.04	Structure	Structure
G.h4s6	352	S	G.h4s6.08	Structure	Structure
G.h4s6	353	G	G.h4s6.09	Structure	Structure
G.h4s6	354	D	G.h4s6.10	Structure	Structure
G.h4s6	355	G	G.h4s6.11	Structure	Structure
G.h4s6	356	R	G.h4s6.12	Structure	Structure
G.h4s6	357	H	G.h4s6.13	Structure	Structure
G.h4s6	358	Y	G.h4s6.20	Structure	Structure
G.S6	359	C	G.S6.01	Structure	Structure
G.S6	360	Y	G.S6.02	Structure	Structure
G.S6	361	P	G.S6.03	Structure	Structure
G.S6	362	H	G.S6.04	Structure	Structure
G.S6	363	F	G.S6.05	Structure	Structure
G.s6h5	364	T	G.s6h5.01	Structure	Structure
G.s6h5	365	C	G.s6h5.02	Structure	Structure
G.s6h5	366	A	G.s6h5.03	Structure	Structure
G.s6h5	367	V	G.s6h5.04	Structure	Structure
G.s6h5	368	D	G.s6h5.05	Structure	Structure
G.H5	369	T	G.H5.01	Structure	Structure
G.H5	370	E	G.H5.02	Structure	Structure
G.H5	371	N	G.H5.03	Structure	Structure
G.H5	372	I	G.H5.04	Structure	Structure
G.H5	373	R	G.H5.05	Structure	Structure
G.H5	374	R	G.H5.06	Structure	Structure
G.H5	375	V	G.H5.07	Structure	Structure
G.H5	376	F	G.H5.08	Structure	Structure
G.H5	377	N	G.H5.09	Structure	Structure
G.H5	378	D	G.H5.10	Structure	Structure
G.H5	379	C	G.H5.11	Structure	Structure
G.H5	380	R	G.H5.12	Structure	Structure
G.H5	381	D	G.H5.13	Structure	Structure
G.H5	382	I	G.H5.14	Structure	Structure
G.H5	383	I	G.H5.15	Structure	Structure
G.H5	384	Q	G.H5.16	Structure	Structure
G.H5	385	R	G.H5.17	Structure	Structure
G.H5	386	M	G.H5.18	Structure	Structure
G.H5	387	H	G.H5.19	Structure	Structure
G.H5	388	L	G.H5.20	Structure	Structure
G.H5	389	R	G.H5.21	Structure	Structure
G.H5	390	Q	G.H5.22	Structure	Structure
G.H5	391	Y	G.H5.23	Structure	Structure
G.H5	392	E	G.H5.24	Structure	Structure
G.H5	393	L	G.H5.25	Structure	Structure
G.H5	394	L	G.H5.26	Structure	Structure

REFINED GPCR RESIDUES

Residue backbones - 265 from structure (63.9%), 150 from model (36.1%)
Residue sidechains - 22 from structure (5.3%), 393 from model (94.7%)

Showing 1 to 415 of 415 entries

Search:

Segment	Seq.num.	AA	GPCRdb#	Backbone from	Sidechain from

N-term	1	M	-	AF2	AF2
N-term	2	D	-	AF2	AF2
N-term	3	R	-	AF2	AF2
N-term	4	R	-	AF2	AF2
N-term	5	M	-	AF2	AF2
N-term	6	W	-	AF2	AF2
N-term	7	G	-	AF2	AF2
N-term	8	A	-	AF2	AF2
N-term	9	H	-	AF2	AF2
N-term	10	V	-	AF2	AF2
N-term	11	F	-	AF2	AF2
N-term	12	C	-	AF2	AF2
N-term	13	V	-	AF2	AF2
N-term	14	L	-	AF2	AF2
N-term	15	S	-	AF2	AF2
N-term	16	P	-	AF2	AF2
N-term	17	L	-	AF2	AF2
N-term	18	P	-	AF2	AF2
N-term	19	T	-	AF2	AF2
N-term	20	V	-	AF2	AF2
N-term	21	L	-	AF2	AF2
N-term	22	G	-	AF2	AF2
N-term	23	H	-	AF2	AF2
N-term	24	M	-	AF2	AF2
N-term	25	H	-	AF2	AF2
N-term	26	P	-	AF2	AF2
N-term	27	E	-	AF2	AF2
N-term	28	C	-	AF2	AF2
N-term	29	D	-	AF2	AF2
N-term	30	F	-	AF2	AF2
N-term	31	I	-	AF2	AF2
N-term	32	T	-	AF2	AF2
N-term	33	Q	-	AF2	AF2
N-term	34	L	-	AF2	AF2
N-term	35	R	-	AF2	AF2
N-term	36	E	-	AF2	AF2
N-term	37	D	-	AF2	AF2
N-term	38	E	-	AF2	AF2
N-term	39	S	-	AF2	AF2
N-term	40	A	-	AF2	AF2
N-term	41	C	-	AF2	AF2
N-term	42	L	-	AF2	AF2
N-term	43	Q	-	AF2	AF2
N-term	44	A	-	AF2	AF2
N-term	45	A	-	AF2	AF2
N-term	46	E	-	AF2	AF2
N-term	47	E	-	AF2	AF2
N-term	48	M	-	AF2	AF2
N-term	49	P	-	AF2	AF2
N-term	50	N	-	AF2	AF2
N-term	51	T	-	AF2	AF2
N-term	52	T	-	AF2	AF2
N-term	53	L	-	AF2	AF2
N-term	54	G	-	AF2	AF2
N-term	55	C	-	Structure	AF2
N-term	56	P	-	Structure	AF2
N-term	57	A	-	Structure	AF2
N-term	58	T	-	Structure	AF2
N-term	59	W	-	Structure	AF2
N-term	60	D	-	Structure	AF2
N-term	61	G	-	Structure	AF2
N-term	62	L	-	Structure	AF2
N-term	63	L	-	Structure	AF2
N-term	64	C	-	Structure	AF2
N-term	65	W	-	Structure	AF2
N-term	66	P	-	Structure	AF2
N-term	67	T	-	Structure	AF2
N-term	68	A	-	Structure	AF2
N-term	69	G	-	Structure	AF2
N-term	70	S	-	Structure	AF2
N-term	71	G	-	Structure	AF2
N-term	72	E	-	Structure	AF2
N-term	73	W	-	Structure	AF2
N-term	74	V	-	Structure	AF2
N-term	75	T	-	Structure	AF2
N-term	76	L	-	Structure	AF2
N-term	77	P	-	Structure	AF2
N-term	78	C	-	Structure	AF2
N-term	79	P	-	Structure	AF2
N-term	80	D	-	Structure	AF2
N-term	81	F	-	Structure	Structure
N-term	82	F	-	Structure	AF2
N-term	83	S	-	Structure	AF2
N-term	84	H	-	Structure	AF2
N-term	85	F	-	Structure	AF2
N-term	86	S	-	Structure	AF2
N-term	87	S	-	Structure	AF2
N-term	88	E	-	Structure	AF2
N-term	89	S	-	Structure	AF2
N-term	90	G	-	Structure	AF2
N-term	91	A	-	Structure	AF2
N-term	92	V	-	Structure	AF2
N-term	93	K	-	Structure	AF2
N-term	94	R	-	Structure	AF2
N-term	95	D	-	Structure	AF2
N-term	96	C	-	Structure	AF2
N-term	97	T	-	Structure	AF2
N-term	98	I	-	Structure	AF2
N-term	99	T	-	Structure	AF2
N-term	100	G	-	Structure	AF2
N-term	101	W	-	Structure	AF2
N-term	102	S	-	Structure	AF2
N-term	103	E	-	Structure	AF2
N-term	104	P	-	Structure	AF2
N-term	105	F	-	Structure	Structure
N-term	106	P	-	Structure	AF2
N-term	107	P	-	Structure	AF2
N-term	108	Y	-	Structure	AF2
N-term	109	P	-	Structure	AF2
N-term	110	V	-	Structure	AF2
N-term	111	A	-	Structure	AF2
N-term	112	C	-	Structure	AF2
N-term	113	P	-	Structure	AF2
N-term	114	V	-	Structure	AF2
N-term	115	P	-	Structure	AF2
TM1	116	L	1.26x26	Structure	AF2
TM1	117	E	1.27x27	Structure	AF2
TM1	118	L	1.28x28	Structure	AF2
TM1	119	L	1.29x29	Structure	AF2
TM1	120	A	1.30x30	Structure	Structure
TM1	121	E	1.31x31	Structure	AF2
TM1	122	E	1.32x32	Structure	AF2
TM1	123	E	1.33x33	Structure	AF2
TM1	124	S	1.34x34	Structure	AF2
TM1	125	Y	1.35x35	Structure	AF2
TM1	126	F	1.36x36	Structure	AF2
TM1	127	S	1.37x37	Structure	AF2
TM1	128	T	1.38x38	Structure	Structure
TM1	129	V	1.39x39	Structure	AF2
TM1	130	K	1.40x40	Structure	AF2
TM1	131	I	1.41x41	Structure	AF2
TM1	132	I	1.42x42	Structure	AF2
TM1	133	Y	1.43x43	Structure	AF2
TM1	134	T	1.44x44	Structure	AF2
TM1	135	V	1.45x45	Structure	AF2
TM1	136	G	1.46x46	Structure	AF2
TM1	137	H	1.47x47	Structure	AF2
TM1	138	S	1.48x48	Structure	AF2
TM1	139	I	1.49x49	Structure	AF2
TM1	140	S	1.50x50	Structure	AF2
TM1	141	I	1.51x51	Structure	AF2
TM1	142	V	1.52x52	Structure	Structure
TM1	143	A	1.53x53	Structure	Structure
TM1	144	L	1.54x54	Structure	AF2
TM1	145	F	1.55x55	Structure	AF2
TM1	146	V	1.56x56	Structure	AF2
TM1	147	A	1.57x57	Structure	AF2
TM1	148	I	1.58x58	Structure	AF2
TM1	149	T	1.59x59	Structure	Structure
TM1	150	I	1.60x60	Structure	AF2
TM1	151	L	1.61x61	Structure	AF2
TM1	152	V	1.62x62	Structure	AF2
TM1	153	A	1.63x63	Structure	AF2
TM1	154	L	1.64x64	Structure	AF2
ICL1	155	R	12.48x48	Structure	AF2
ICL1	156	R	12.49x49	Structure	AF2
ICL1	157	L	12.50x50	Structure	Structure
ICL1	158	H	12.51x51	Structure	AF2
TM2	159	C	2.44x44	Structure	AF2
TM2	160	P	2.45x45	Structure	AF2
TM2	161	R	2.46x46	Structure	AF2
TM2	162	N	2.47x47	Structure	AF2
TM2	163	Y	2.48x48	Structure	AF2
TM2	164	V	2.49x49	Structure	AF2
TM2	165	H	2.50x50	Structure	AF2
TM2	166	T	2.51x51	Structure	AF2
TM2	167	Q	2.52x52	Structure	AF2
TM2	168	L	2.53x53	Structure	AF2
TM2	169	F	2.54x54	Structure	AF2
TM2	170	T	2.55x55	Structure	Structure
TM2	171	T	2.56x56	Structure	AF2
TM2	172	F	2.57x57	Structure	AF2
TM2	173	I	2.58x58	Structure	AF2
TM2	174	L	2.59x59	Structure	AF2
TM2	175	K	2.60x60	Structure	AF2
TM2	176	A	2.61x61	Structure	AF2
TM2	177	G	2.62x62	Structure	AF2
TM2	178	A	2.63x63	Structure	AF2
TM2	179	V	2.64x64	Structure	AF2
TM2	180	F	2.65x65	Structure	AF2
TM2	181	L	2.66x66	Structure	Structure
TM2	182	K	2.67x67	Structure	AF2
TM2	183	D	2.68x68	Structure	AF2
TM2	184	A	2.69x69	Structure	Structure
TM2	185	A	2.70x70	Structure	AF2
TM2	186	L	2.71x71	Structure	AF2
TM2	187	F	2.72x72	Structure	AF2
ECL1	188	H	-	Structure	AF2
ECL1	189	S	-	Structure	AF2
ECL1	190	D	-	Structure	AF2
ECL1	191	D	-	Structure	AF2
ECL1	192	T	-	Structure	AF2
ECL1	193	D	-	Structure	AF2
ECL1	194	H	-	Structure	AF2
ECL1	195	C	-	Structure	AF2
ECL1	196	S	-	Structure	AF2
ECL1	197	F	-	Structure	AF2
ECL1	198	S	-	Structure	Structure
TM3	199	T	3.26x26	Structure	AF2
TM3	200	V	3.27x27	Structure	AF2
TM3	201	L	3.28x28	Structure	Structure
TM3	202	C	3.29x29	Structure	AF2
TM3	203	K	3.30x30	Structure	AF2
TM3	204	V	3.31x31	Structure	AF2
TM3	205	S	3.32x32	Structure	AF2
TM3	206	V	3.33x33	Structure	AF2
TM3	207	A	3.34x34	Structure	Structure
TM3	208	A	3.35x35	Structure	AF2
TM3	209	S	3.36x36	Structure	AF2
TM3	210	H	3.37x37	Structure	AF2
TM3	211	F	3.38x38	Structure	AF2
TM3	212	A	3.39x39	Structure	AF2
TM3	213	T	3.40x40	Structure	AF2
TM3	214	M	3.41x41	Structure	AF2
TM3	215	T	3.42x42	Structure	AF2
TM3	216	N	3.43x43	Structure	AF2
TM3	217	F	3.44x44	Structure	AF2
TM3	218	S	3.45x45	Structure	AF2
TM3	219	W	3.46x46	Structure	Structure
TM3	220	L	3.47x47	Structure	AF2
TM3	221	L	3.48x48	Structure	AF2
TM3	222	A	3.49x49	Structure	AF2
TM3	223	E	3.50x50	Structure	AF2
TM3	224	A	3.51x51	Structure	AF2
TM3	225	V	3.52x52	Structure	AF2
TM3	226	Y	3.53x53	Structure	AF2
TM3	227	L	3.54x54	Structure	Structure
TM3	228	N	3.55x55	Structure	AF2
TM3	229	C	3.56x56	Structure	AF2
TM3	230	L	3.57x57	Structure	AF2
TM3	231	L	3.58x58	Structure	AF2
TM3	232	A	3.59x59	Structure	AF2
TM3	233	S	3.60x60	Structure	AF2
ICL2	234	T	-	Structure	AF2
ICL2	235	S	-	Structure	AF2
ICL2	236	P	-	Structure	AF2
ICL2	237	S	-	Structure	AF2
ICL2	238	S	-	Structure	AF2
TM4	239	R	4.39x40	Structure	AF2
TM4	240	R	4.40x41	Structure	AF2
TM4	241	A	4.41x42	Structure	AF2
TM4	242	F	4.42x43	Structure	AF2
TM4	243	W	4.43x44	Structure	AF2
TM4	244	W	4.44x45	Structure	AF2
TM4	245	L	4.45x46	Structure	AF2
TM4	246	V	4.46x47	Structure	AF2
TM4	247	L	4.47x48	Structure	Structure
TM4	248	A	4.48x49	Structure	Structure
TM4	249	G	4.49x491	AF2	AF2
TM4	250	W	4.50x50	AF2	AF2
TM4	251	G	4.51x51	AF2	AF2
TM4	252	L	4.52x52	AF2	AF2
TM4	253	P	4.53x53	AF2	AF2
TM4	254	V	4.54x54	AF2	AF2
TM4	255	L	4.55x55	AF2	AF2
TM4	256	F	4.56x56	AF2	AF2
TM4	257	T	4.57x57	AF2	AF2
TM4	258	G	4.58x58	Structure	Structure
TM4	259	T	4.59x59	Structure	Structure
TM4	260	W	4.60x60	Structure	AF2
TM4	261	V	4.61x61	Structure	AF2
TM4	262	S	4.62x62	Structure	AF2
TM4	263	C	4.63x63	Structure	AF2
TM4	264	K	4.64x64	Structure	AF2
TM4	265	L	4.65x65	Structure	AF2
TM4	266	A	4.66x66	Structure	AF2
TM4	267	F	4.67x67	Structure	AF2
TM4	268	E	4.68x68	Structure	AF2
ECL2	269	D	-	Structure	AF2
ECL2	270	I	-	Structure	AF2
ECL2	271	A	-	Structure	AF2
ECL2	272	C	45.50x50	Structure	AF2
ECL2	273	W	45.51x51	Structure	AF2
ECL2	274	D	45.52x52	Structure	AF2
ECL2	275	L	-	Structure	AF2
ECL2	276	D	-	Structure	AF2
ECL2	277	D	-	Structure	AF2
ECL2	278	T	-	Structure	AF2
ECL2	279	S	-	Structure	AF2
ECL2	280	P	-	Structure	AF2
ECL2	281	Y	-	Structure	AF2
TM5	282	W	5.36x37	Structure	AF2
TM5	283	W	5.37x38	Structure	AF2
TM5	284	I	5.38x381	Structure	AF2
TM5	285	I	5.39x39	Structure	AF2
TM5	286	K	5.40x40	Structure	AF2
TM5	287	G	5.41x41	Structure	AF2
TM5	288	P	5.42x42	Structure	AF2
TM5	289	I	5.43x43	Structure	AF2
TM5	290	V	5.44x44	Structure	AF2
TM5	291	L	5.45x45	Structure	AF2
TM5	292	S	5.46x46	Structure	AF2
TM5	293	V	5.47x47	Structure	AF2
TM5	294	G	5.48x48	Structure	AF2
TM5	295	V	5.49x49	Structure	AF2
TM5	296	N	5.50x50	Structure	AF2
TM5	297	F	5.51x51	Structure	AF2
TM5	298	G	5.52x52	Structure	AF2
TM5	299	L	5.53x53	Structure	AF2
TM5	300	F	5.54x54	Structure	AF2
TM5	301	L	5.55x55	Structure	AF2
TM5	302	N	5.56x56	Structure	AF2
TM5	303	I	5.57x57	Structure	AF2
TM5	304	I	5.58x58	Structure	AF2
TM5	305	R	5.59x59	Structure	AF2
TM5	306	I	5.60x60	Structure	AF2
TM5	307	L	5.61x61	Structure	AF2
TM5	308	V	5.62x62	Structure	Structure
TM5	309	R	5.63x63	Structure	AF2
TM5	310	K	5.64x64	Structure	AF2
TM5	311	L	5.65x65	Structure	Structure
ICL3	312	E	-	Structure	AF2
ICL3	313	P	-	Structure	AF2
ICL3	314	A	-	Structure	AF2
ICL3	315	Q	-	Structure	AF2
ICL3	316	G	-	Structure	AF2
ICL3	317	S	-	Structure	AF2
ICL3	318	L	-	Structure	AF2
TM6	319	H	6.30x30	Structure	AF2
TM6	320	T	6.31x31	Structure	AF2
TM6	321	Q	6.32x32	Structure	AF2
TM6	322	S	6.33x33	Structure	AF2
TM6	323	Q	6.34x34	Structure	AF2
TM6	324	Y	6.35x35	Structure	AF2
TM6	325	W	6.36x36	Structure	AF2
TM6	326	R	6.37x37	Structure	AF2
TM6	327	L	6.38x38	Structure	AF2
TM6	328	S	6.39x39	Structure	AF2
TM6	329	K	6.40x40	AF2	AF2
TM6	330	S	6.41x41	AF2	AF2
TM6	331	T	6.42x42	AF2	AF2
TM6	332	L	6.43x43	AF2	AF2
TM6	333	F	6.44x44	AF2	AF2
TM6	334	L	6.45x45	AF2	AF2
TM6	335	I	6.46x46	AF2	AF2
TM6	336	P	6.47x47	AF2	AF2
TM6	337	L	6.48x48	AF2	AF2
TM6	338	F	6.49x49	AF2	AF2
TM6	339	G	6.50x50	AF2	AF2
TM6	340	I	6.51x51	AF2	AF2
TM6	341	H	6.52x52	AF2	AF2
TM6	342	Y	6.53x53	AF2	AF2
TM6	343	I	6.54x54	AF2	AF2
TM6	344	I	6.55x55	AF2	AF2
TM6	345	F	6.56x56	AF2	AF2
TM6	346	N	6.57x57	AF2	AF2
TM6	347	F	6.58x58	AF2	AF2
TM6	348	L	6.59x59	AF2	AF2
ECL3	349	P	-	AF2	AF2
ECL3	350	D	-	AF2	AF2
ECL3	351	N	-	AF2	AF2
ECL3	352	A	-	AF2	AF2
TM7	353	G	7.34x33	AF2	AF2
TM7	354	L	7.35x34	AF2	AF2
TM7	355	G	7.36x35	AF2	AF2
TM7	356	I	7.37x36	AF2	AF2
TM7	357	R	7.38x37	AF2	AF2
TM7	358	L	7.39x38	AF2	AF2
TM7	359	P	7.40x39	AF2	AF2
TM7	360	L	7.41x40	AF2	AF2
TM7	361	E	7.42x41	AF2	AF2
TM7	362	L	7.43x42	AF2	AF2
TM7	363	G	7.44x43	AF2	AF2
TM7	364	L	7.45x44	AF2	AF2
TM7	365	G	7.46x45	AF2	AF2
TM7	366	S	7.47x46	AF2	AF2
TM7	367	F	7.48x47	AF2	AF2
TM7	368	Q	7.49x49	AF2	AF2
TM7	369	G	7.50x50	AF2	AF2
TM7	370	F	7.51x51	AF2	AF2
TM7	371	I	7.52x52	AF2	AF2
TM7	372	V	7.53x53	AF2	AF2
TM7	373	A	7.54x54	AF2	AF2
TM7	374	I	7.55x55	AF2	AF2
TM7	375	L	7.56x56	AF2	AF2
TM7	376	Y	7.57x57	AF2	AF2
TM7	377	C	7.58x58	AF2	AF2
TM7	378	F	7.59x59	AF2	AF2
TM7	379	L	7.60x60	AF2	AF2
H8	380	N	8.47x47	AF2	AF2
H8	381	Q	8.48x48	AF2	AF2
H8	382	E	8.49x49	AF2	AF2
H8	383	V	8.50x50	AF2	AF2
H8	384	R	8.51x51	AF2	AF2
H8	385	T	8.52x52	AF2	AF2
H8	386	E	8.53x53	AF2	AF2
H8	387	I	8.54x54	AF2	AF2
H8	388	S	8.55x55	AF2	AF2
H8	389	R	8.56x56	AF2	AF2
H8	390	K	8.57x57	AF2	AF2
H8	391	W	8.58x58	AF2	AF2
H8	392	H	8.59x59	AF2	AF2
H8	393	G	8.60x60	AF2	AF2
H8	394	H	8.61x61	AF2	AF2
H8	395	D	8.62x62	AF2	AF2
H8	396	P	8.63x63	AF2	AF2
H8	397	E	8.64x64	AF2	AF2
H8	398	L	8.65x65	AF2	AF2
H8	399	L	8.66x66	AF2	AF2
H8	400	P	8.67x67	AF2	AF2
H8	401	A	8.68x68	AF2	AF2
H8	402	W	8.69x69	AF2	AF2
H8	403	R	8.70x70	AF2	AF2
H8	404	T	8.71x71	AF2	AF2
H8	405	R	8.72x72	AF2	AF2
C-term	406	A	-	AF2	AF2
C-term	407	K	-	AF2	AF2
C-term	408	W	-	AF2	AF2
C-term	409	T	-	AF2	AF2
C-term	410	T	-	AF2	AF2
C-term	411	P	-	AF2	AF2
C-term	412	S	-	AF2	AF2
C-term	413	R	-	AF2	AF2
C-term	414	S	-	AF2	AF2
C-term	415	A	-	AF2	AF2

GPCR - G protein interface interactions

The biflare plot is a modified version of a flareplot, where lines are drawn between an inner concentric circle (Gα residues) and an outer concentric circle (GPCR residues) depicting the interface interactions.
Different interaction types are shown with different line types (aromatic - solid, hydrophobic - dashed, ionic - long dashed, polar - dotted, Van der Waals - dash-dot).
The interactive features include filtering on interaction type, segments, residues and backbone or sidechain interactions.

Interaction cut-off:

Residue numbering:

GPCR-G protein backbone (bb) or sidechain (sc):

bb-bb

bb-sc

sc-sc

sc-bb

Structures

Sequence Color

Gα, Gβ, Gγ, GPCR
Interaction cut-off: strict (stick), loose (line)

NGL is a WebGL based 3D viewer powered by MMTF.

Search:

Interaction type	GPCR Segment	AA	Number	Generic number	Gα segment	AA	Number	Generic number

Interaction type	GPCR Segment	AA	Number	Generic number	Gα segment	AA	Number	Generic number

Aromatic	TM4	R	239	4x40	G.H5	Y	391	G.H5.23
Aromatic	TM2	F	172	2x57	G.S1	H	41	G.S1.02
Aromatic	TM2	Y	163	2x48	G.H5	Y	391	G.H5.23
Hydrophobic	H8	H	392	8x59	G.HN	K	8	G.HN.24
Hydrophobic	TM2	F	172	2x57	G.h2s4	T	242	G.h2s4.05
Hydrophobic	TM4	R	239	4x40	G.H5	Y	391	G.H5.23
Hydrophobic	H8	D	395	8x62	G.HN	R	13	G.HN.30
Hydrophobic	TM4	V	246	4x47	G.H5	L	388	G.H5.20
Hydrophobic	H8	E	397	8x64	G.HN	K	17	G.HN.34
Hydrophobic	H8	L	398	8x65	G.HN	R	20	G.HN.37
Hydrophobic	TM4	W	243	4x44	G.H5	L	394	G.H5.26
Hydrophobic	TM2	T	171	2x56	G.S3	V	217	G.S3.01
Hydrophobic	TM4	W	243	4x44	G.H5	L	388	G.H5.20
Hydrophobic	TM2	F	172	2x57	G.H5	M	386	G.H5.18
Hydrophobic	H8	P	396	8x63	G.HN	R	13	G.HN.30
Hydrophobic	TM4	V	254	4x54	G.H5	L	394	G.H5.26
Hydrophobic	H8	W	391	8x58	G.HN	K	8	G.HN.24
Hydrophobic	H8	H	394	8x61	G.HN	N	6	G.HN.22
Hydrophobic	H8	K	390	8x57	G.HN	N	6	G.HN.22
Hydrophobic	H8	H	394	8x61	G.HN	K	8	G.HN.24
Hydrophobic	TM4	V	246	4x47	G.H5	R	385	G.H5.17
Hydrophobic	ECL2	I	270	-	G.H5	L	393	G.H5.25
Hydrophobic	TM4	R	239	4x40	G.H5	L	393	G.H5.25
Hydrophobic	TM2	K	175	2x60	G.HN	Q	35	G.HN.52
Hydrophobic	TM4	W	250	4x50	G.h4s6	Y	358	G.h4s6.20
Hydrophobic	TM4	A	266	4x66	G.H5	L	393	G.H5.25
Hydrophobic	TM2	F	172	2x57	G.S1	H	41	G.S1.02
Hydrophobic	TM4	L	247	4x48	G.H5	L	394	G.H5.26
Hydrophobic	N-term	W	101	-	G.H5	Y	391	G.H5.23
Hydrophobic	TM2	T	166	2x51	G.H5	H	387	G.H5.19
Hydrophobic	H8	H	394	8x61	G.HN	S	7	G.HN.23
Hydrophobic	TM4	W	243	4x44	G.H5	L	393	G.H5.25
Hydrophobic	TM2	I	173	2x58	G.hns1	R	38	G.hns1.02
Hydrophobic	TM4	F	242	4x43	G.H5	L	388	G.H5.20
Hydrophobic	TM2	T	170	2x55	G.S3	V	217	G.S3.01
Hydrophobic	H8	L	398	8x65	G.HN	E	16	G.HN.33
Hydrophobic	TM2	T	171	2x56	G.S1	H	41	G.S1.02
Hydrophobic	H8	D	395	8x62	G.HN	K	8	G.HN.24
Hydrophobic	TM2	T	170	2x55	G.H5	F	376	G.H5.08
Hydrophobic	TM4	F	242	4x43	G.H5	Q	384	G.H5.16
Hydrophobic	ECL2	W	273	45x51	G.H5	L	393	G.H5.25
Hydrophobic	TM2	F	172	2x57	G.hns1	R	38	G.hns1.02
Hydrophobic	ECL2	W	273	45x51	G.H5	Y	391	G.H5.23
Hydrophobic	TM2	T	170	2x55	G.H5	R	380	G.H5.12
Hydrophobic	TM2	F	172	2x57	G.H5	I	383	G.H5.15
Hydrophobic	TM2	Q	167	2x52	G.H5	L	388	G.H5.20
Hydrophobic	TM2	Y	163	2x48	G.H5	Y	391	G.H5.23
Hydrophobic	TM4	V	246	4x47	G.H5	L	394	G.H5.26
Hydrophobic	TM4	W	250	4x50	G.H5	R	385	G.H5.17
Hydrophobic	TM2	Q	167	2x52	G.H5	Q	384	G.H5.16
Ionic	H8	D	395	8x62	G.HN	R	13	G.HN.30
Ionic	H8	E	397	8x64	G.HN	K	17	G.HN.34
Ionic	H8	D	395	8x62	G.HN	K	8	G.HN.24
Polar	H8	H	392	8x59	G.HN	K	8	G.HN.24
Polar	H8	D	395	8x62	G.HN	R	13	G.HN.30
Polar	H8	H	394	8x61	G.HN	R	13	G.HN.30
Polar	H8	E	397	8x64	G.HN	K	17	G.HN.34
Polar	H8	W	391	8x58	G.HN	K	8	G.HN.24
Polar	H8	H	394	8x61	G.HN	N	6	G.HN.22
Polar	H8	K	390	8x57	G.HN	N	6	G.HN.22
Polar	H8	H	394	8x61	G.HN	K	8	G.HN.24
Polar	TM4	V	246	4x47	G.H5	R	385	G.H5.17
Polar	TM2	T	171	2x56	G.hns1	A	39	G.hns1.03
Polar	H8	H	394	8x61	G.HN	S	7	G.HN.23
Polar	ICL3	S	317	-	G.H5	E	392	G.H5.24
Polar	TM4	S	262	4x62	G.H5	L	394	G.H5.26
Polar	TM2	Q	167	2x52	G.H5	Q	384	G.H5.16
Van-der-waals	H8	H	392	8x59	G.HN	K	8	G.HN.24
Van-der-waals	H8	D	395	8x62	G.HN	R	13	G.HN.30
Van-der-waals	TM4	V	246	4x47	G.H5	L	388	G.H5.20
Van-der-waals	H8	H	394	8x61	G.HN	R	13	G.HN.30
Van-der-waals	H8	E	397	8x64	G.HN	K	17	G.HN.34
Van-der-waals	H8	L	398	8x65	G.HN	R	20	G.HN.37
Van-der-waals	TM4	W	243	4x44	G.H5	L	394	G.H5.26
Van-der-waals	TM2	T	171	2x56	G.S3	V	217	G.S3.01
Van-der-waals	TM4	W	243	4x44	G.H5	L	388	G.H5.20
Van-der-waals	TM2	F	172	2x57	G.H5	M	386	G.H5.18
Van-der-waals	TM4	V	254	4x54	G.H5	L	394	G.H5.26
Van-der-waals	H8	W	391	8x58	G.HN	K	8	G.HN.24
Van-der-waals	H8	H	394	8x61	G.HN	N	6	G.HN.22
Van-der-waals	H8	K	390	8x57	G.HN	N	6	G.HN.22
Van-der-waals	H8	H	394	8x61	G.HN	K	8	G.HN.24
Van-der-waals	TM4	V	246	4x47	G.H5	R	385	G.H5.17
Van-der-waals	TM4	R	239	4x40	G.H5	L	393	G.H5.25
Van-der-waals	TM2	K	175	2x60	G.HN	Q	35	G.HN.52
Van-der-waals	TM4	W	250	4x50	G.h4s6	Y	358	G.h4s6.20
Van-der-waals	TM4	A	266	4x66	G.H5	L	393	G.H5.25
Van-der-waals	TM2	F	172	2x57	G.S1	H	41	G.S1.02
Van-der-waals	TM2	T	166	2x51	G.H5	H	387	G.H5.19
Van-der-waals	H8	H	394	8x61	G.HN	S	7	G.HN.23
Van-der-waals	TM4	W	243	4x44	G.H5	L	393	G.H5.25
Van-der-waals	TM2	I	173	2x58	G.hns1	R	38	G.hns1.02
Van-der-waals	TM4	F	242	4x43	G.H5	L	388	G.H5.20
Van-der-waals	TM2	T	170	2x55	G.S3	V	217	G.S3.01
Van-der-waals	H8	L	398	8x65	G.HN	E	16	G.HN.33
Van-der-waals	TM2	T	171	2x56	G.S1	H	41	G.S1.02
Van-der-waals	H8	D	395	8x62	G.HN	K	8	G.HN.24
Van-der-waals	TM4	F	242	4x43	G.H5	Q	384	G.H5.16
Van-der-waals	TM4	S	262	4x62	G.H5	L	394	G.H5.26
Van-der-waals	TM2	F	172	2x57	G.hns1	R	38	G.hns1.02
Van-der-waals	TM2	F	172	2x57	G.H5	I	383	G.H5.15
Van-der-waals	TM2	Q	167	2x52	G.H5	L	388	G.H5.20
Van-der-waals	TM2	Y	163	2x48	G.H5	Y	391	G.H5.23
Van-der-waals	TM4	V	246	4x47	G.H5	L	394	G.H5.26
Van-der-waals	H8	W	391	8x58	G.HN	Q	12	G.HN.29
Van-der-waals	TM2	K	175	2x60	G.HN	Q	31	G.HN.48
Van-der-waals	TM2	Q	167	2x52	G.H5	Q	384	G.H5.16

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Main reference

Refined structure (7V9M) of Gs - GHRH receptor Download Full

GPCR CLASS (FAMILY)

SPECIES

G PROTEIN FAMILY

DATE

3D VIEW

REFINED G PROTEIN RESIDUES

REFINED GPCR RESIDUES

GPCR - G protein interface interactions

Structures

Refined structure (7V9M) of G_s - GHRH receptor

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