Biased Signaling Atlas

Refined structure (8J6D) of G_o - C3a receptor

Full

GPCR CLASS (FAMILY)

A (Rhodopsin)

SPECIES

Homo sapiens

G PROTEIN FAMILY

G_i/o

DATE

2024-07-12

3D VIEW

NGL is a WebGL based 3D viewer powered by MMTF.

Structure

GPCR

Gα

Gβ

Gγ
Model

AlphaFold2-Multimer

REFINED G PROTEIN RESIDUES

Residue backbones - 210 from structure (59.3%), 144 from model (40.7%)
Residue sidechains - 179 from structure (50.6%), 175 from model (49.4%)

Showing 1 to 354 of 354 entries

Search:

Segment	Seq.num.	AA	CGN#	Backbone from	Sidechain from
	:

Segment	Seq.num.	AA	CGN#	Backbone from	Sidechain from

G.HN	1	M	G.HN.01	AF2	AF2
G.HN	2	G	G.HN.02	AF2	AF2
G.HN	3	C	G.HN.09	AF2	AF2
G.HN	4	T	G.HN.10	AF2	AF2
G.HN	5	L	G.HN.11	AF2	AF2
G.HN	6	S	G.HN.30	Structure	Structure
G.HN	7	A	G.HN.31	Structure	Structure
G.HN	8	E	G.HN.32	Structure	Structure
G.HN	9	E	G.HN.33	Structure	Structure
G.HN	10	R	G.HN.34	Structure	Structure
G.HN	11	A	G.HN.35	Structure	Structure
G.HN	12	A	G.HN.36	Structure	Structure
G.HN	13	L	G.HN.37	Structure	Structure
G.HN	14	E	G.HN.38	Structure	Structure
G.HN	15	R	G.HN.39	Structure	Structure
G.HN	16	S	G.HN.40	Structure	Structure
G.HN	17	K	G.HN.41	Structure	Structure
G.HN	18	A	G.HN.42	Structure	Structure
G.HN	19	I	G.HN.43	Structure	Structure
G.HN	20	E	G.HN.44	Structure	AF2
G.HN	21	K	G.HN.45	Structure	Structure
G.HN	22	N	G.HN.46	Structure	Structure
G.HN	23	L	G.HN.47	Structure	Structure
G.HN	24	K	G.HN.48	Structure	Structure
G.HN	25	E	G.HN.49	Structure	AF2
G.HN	26	D	G.HN.50	Structure	Structure
G.HN	27	G	G.HN.51	Structure	Structure
G.HN	28	I	G.HN.52	Structure	Structure
G.HN	29	S	G.HN.53	Structure	AF2
G.hns1	30	A	G.hns1.01	Structure	Structure
G.hns1	31	A	G.hns1.02	Structure	Structure
G.hns1	32	K	G.hns1.03	Structure	Structure
G.S1	33	D	G.S1.01	Structure	AF2
G.S1	34	V	G.S1.02	Structure	Structure
G.S1	35	K	G.S1.03	Structure	Structure
G.S1	36	L	G.S1.04	Structure	Structure
G.S1	37	L	G.S1.05	Structure	Structure
G.S1	38	L	G.S1.06	Structure	Structure
G.S1	39	L	G.S1.07	Structure	Structure
G.s1h1	40	G	G.s1h1.01	Structure	Structure
G.s1h1	41	A	G.s1h1.02	Structure	Structure
G.s1h1	42	G	G.s1h1.03	Structure	AF2
G.s1h1	43	E	G.s1h1.04	Structure	AF2
G.s1h1	44	S	G.s1h1.05	Structure	Structure
G.s1h1	45	G	G.s1h1.06	Structure	Structure
G.H1	46	K	G.H1.01	Structure	Structure
G.H1	47	S	G.H1.02	Structure	Structure
G.H1	48	T	G.H1.03	Structure	Structure
G.H1	49	I	G.H1.04	Structure	Structure
G.H1	50	V	G.H1.05	Structure	Structure
G.H1	51	K	G.H1.06	Structure	AF2
G.H1	52	Q	G.H1.07	Structure	AF2
G.H1	53	M	G.H1.08	Structure	Structure
G.H1	54	K	G.H1.09	Structure	AF2
G.H1	55	I	G.H1.10	Structure	Structure
G.H1	56	I	G.H1.11	AF2	AF2
G.H1	57	H	G.H1.12	AF2	AF2
G.h1ha	58	E	G.h1ha.01	AF2	AF2
G.h1ha	59	D	G.h1ha.02	AF2	AF2
G.h1ha	60	G	G.h1ha.03	AF2	AF2
G.h1ha	61	F	G.h1ha.04	AF2	AF2
G.h1ha	62	S	G.h1ha.05	AF2	AF2
H.HA	63	G	H.HA.01	AF2	AF2
H.HA	64	E	H.HA.02	AF2	AF2
H.HA	65	D	H.HA.03	AF2	AF2
H.HA	66	V	H.HA.04	AF2	AF2
H.HA	67	K	H.HA.05	AF2	AF2
H.HA	68	Q	H.HA.06	AF2	AF2
H.HA	69	Y	H.HA.07	AF2	AF2
H.HA	70	K	H.HA.08	AF2	AF2
H.HA	71	P	H.HA.09	AF2	AF2
H.HA	72	V	H.HA.10	AF2	AF2
H.HA	73	V	H.HA.11	AF2	AF2
H.HA	74	Y	H.HA.12	AF2	AF2
H.HA	75	S	H.HA.13	AF2	AF2
H.HA	76	N	H.HA.14	AF2	AF2
H.HA	77	T	H.HA.15	AF2	AF2
H.HA	78	I	H.HA.16	AF2	AF2
H.HA	79	Q	H.HA.17	AF2	AF2
H.HA	80	S	H.HA.18	AF2	AF2
H.HA	81	L	H.HA.19	AF2	AF2
H.HA	82	A	H.HA.20	AF2	AF2
H.HA	83	A	H.HA.21	AF2	AF2
H.HA	84	I	H.HA.22	AF2	AF2
H.HA	85	V	H.HA.23	AF2	AF2
H.HA	86	R	H.HA.24	AF2	AF2
H.HA	87	A	H.HA.25	AF2	AF2
H.HA	88	M	H.HA.26	AF2	AF2
H.HA	89	D	H.HA.27	AF2	AF2
H.HA	90	T	H.HA.28	AF2	AF2
H.HA	91	L	H.HA.29	AF2	AF2
H.hahb	92	G	H.hahb.01	AF2	AF2
H.hahb	93	I	H.hahb.04	AF2	AF2
H.hahb	94	E	H.hahb.05	AF2	AF2
H.hahb	95	Y	H.hahb.06	AF2	AF2
H.hahb	96	G	H.hahb.07	AF2	AF2
H.hahb	97	D	H.hahb.08	AF2	AF2
H.hahb	98	K	H.hahb.09	AF2	AF2
H.HB	99	E	H.HB.01	AF2	AF2
H.HB	100	R	H.HB.02	AF2	AF2
H.HB	101	K	H.HB.03	AF2	AF2
H.HB	102	A	H.HB.04	AF2	AF2
H.HB	103	D	H.HB.05	AF2	AF2
H.HB	104	A	H.HB.06	AF2	AF2
H.HB	105	K	H.HB.07	AF2	AF2
H.HB	106	M	H.HB.08	AF2	AF2
H.HB	107	V	H.HB.09	AF2	AF2
H.HB	108	C	H.HB.10	AF2	AF2
H.HB	109	D	H.HB.11	AF2	AF2
H.HB	110	V	H.HB.12	AF2	AF2
H.HB	111	V	H.HB.13	AF2	AF2
H.HB	112	S	H.HB.14	AF2	AF2
H.hbhc	113	R	H.hbhc.01	AF2	AF2
H.hbhc	114	M	H.hbhc.02	AF2	AF2
H.hbhc	115	E	H.hbhc.03	AF2	AF2
H.hbhc	116	D	H.hbhc.04	AF2	AF2
H.hbhc	117	T	H.hbhc.05	AF2	AF2
H.hbhc	118	E	H.hbhc.12	AF2	AF2
H.hbhc	119	P	H.hbhc.13	AF2	AF2
H.hbhc	120	F	H.hbhc.14	AF2	AF2
H.hbhc	121	S	H.hbhc.15	AF2	AF2
H.HC	122	A	H.HC.01	AF2	AF2
H.HC	123	E	H.HC.02	AF2	AF2
H.HC	124	L	H.HC.03	AF2	AF2
H.HC	125	L	H.HC.04	AF2	AF2
H.HC	126	S	H.HC.05	AF2	AF2
H.HC	127	A	H.HC.06	AF2	AF2
H.HC	128	M	H.HC.07	AF2	AF2
H.HC	129	M	H.HC.08	AF2	AF2
H.HC	130	R	H.HC.09	AF2	AF2
H.HC	131	L	H.HC.10	AF2	AF2
H.HC	132	W	H.HC.11	AF2	AF2
H.HC	133	G	H.HC.12	AF2	AF2
H.hchd	134	D	H.hchd.01	AF2	AF2
H.HD	135	S	H.HD.01	AF2	AF2
H.HD	136	G	H.HD.02	AF2	AF2
H.HD	137	I	H.HD.03	AF2	AF2
H.HD	138	Q	H.HD.04	AF2	AF2
H.HD	139	E	H.HD.05	AF2	AF2
H.HD	140	C	H.HD.06	AF2	AF2
H.HD	141	F	H.HD.07	AF2	AF2
H.HD	142	N	H.HD.08	AF2	AF2
H.HD	143	R	H.HD.09	AF2	AF2
H.HD	144	S	H.HD.10	AF2	AF2
H.HD	145	R	H.HD.11	AF2	AF2
H.HD	146	E	H.HD.12	AF2	AF2
H.hdhe	147	Y	H.hdhe.01	AF2	AF2
H.hdhe	148	Q	H.hdhe.02	AF2	AF2
H.hdhe	149	L	H.hdhe.03	AF2	AF2
H.hdhe	150	N	H.hdhe.04	AF2	AF2
H.hdhe	151	D	H.hdhe.05	AF2	AF2
H.HE	152	S	H.HE.01	AF2	AF2
H.HE	153	A	H.HE.02	AF2	AF2
H.HE	154	K	H.HE.03	AF2	AF2
H.HE	155	Y	H.HE.04	AF2	AF2
H.HE	156	Y	H.HE.05	AF2	AF2
H.HE	157	L	H.HE.06	AF2	AF2
H.HE	158	D	H.HE.07	AF2	AF2
H.HE	159	S	H.HE.08	AF2	AF2
H.HE	160	L	H.HE.09	AF2	AF2
H.HE	161	D	H.HE.10	AF2	AF2
H.HE	162	R	H.HE.11	AF2	AF2
H.HE	163	I	H.HE.12	AF2	AF2
H.HE	164	G	H.HE.13	AF2	AF2
H.hehf	165	A	H.hehf.01	AF2	AF2
H.hehf	166	A	H.hehf.02	AF2	AF2
H.hehf	167	D	H.hehf.03	AF2	AF2
H.hehf	168	Y	H.hehf.04	AF2	AF2
H.hehf	169	Q	H.hehf.05	AF2	AF2
H.hehf	170	P	H.hehf.06	AF2	AF2
H.hehf	171	T	H.hehf.07	AF2	AF2
H.HF	172	E	H.HF.01	AF2	AF2
H.HF	173	Q	H.HF.02	AF2	AF2
H.HF	174	D	H.HF.03	AF2	AF2
H.HF	175	I	H.HF.04	AF2	AF2
H.HF	176	L	H.HF.05	AF2	AF2
H.HF	177	R	H.HF.06	AF2	AF2
G.hfs2	178	T	G.hfs2.01	AF2	AF2
G.hfs2	179	R	G.hfs2.02	AF2	AF2
G.hfs2	180	V	G.hfs2.03	AF2	AF2
G.hfs2	181	K	G.hfs2.04	AF2	AF2
G.hfs2	182	T	G.hfs2.05	AF2	AF2
G.hfs2	183	T	G.hfs2.06	Structure	Structure
G.hfs2	184	G	G.hfs2.07	Structure	Structure
G.S2	185	I	G.S2.01	Structure	Structure
G.S2	186	V	G.S2.02	Structure	Structure
G.S2	187	E	G.S2.03	Structure	Structure
G.S2	188	T	G.S2.04	Structure	Structure
G.S2	189	H	G.S2.05	Structure	Structure
G.S2	190	F	G.S2.06	Structure	Structure
G.S2	191	T	G.S2.07	Structure	Structure
G.S2	192	F	G.S2.08	Structure	Structure
G.s2s3	193	K	G.s2s3.01	Structure	Structure
G.s2s3	194	N	G.s2s3.02	Structure	Structure
G.S3	195	L	G.S3.01	Structure	Structure
G.S3	196	H	G.S3.02	Structure	Structure
G.S3	197	F	G.S3.03	Structure	Structure
G.S3	198	R	G.S3.04	Structure	Structure
G.S3	199	L	G.S3.05	Structure	Structure
G.S3	200	F	G.S3.06	Structure	Structure
G.S3	201	D	G.S3.07	Structure	Structure
G.S3	202	V	G.S3.08	Structure	Structure
G.s3h2	203	G	G.s3h2.01	Structure	Structure
G.s3h2	204	G	G.s3h2.02	Structure	Structure
G.s3h2	205	Q	G.s3h2.03	Structure	Structure
G.H2	206	R	G.H2.01	Structure	AF2
G.H2	207	S	G.H2.02	Structure	Structure
G.H2	208	E	G.H2.03	Structure	Structure
G.H2	209	R	G.H2.04	Structure	Structure
G.H2	210	K	G.H2.05	Structure	Structure
G.H2	211	K	G.H2.06	Structure	Structure
G.H2	212	W	G.H2.07	Structure	Structure
G.H2	213	I	G.H2.08	Structure	Structure
G.H2	214	H	G.H2.09	Structure	Structure
G.H2	215	C	G.H2.10	Structure	Structure
G.h2s4	216	F	G.h2s4.01	Structure	Structure
G.h2s4	217	E	G.h2s4.02	Structure	Structure
G.h2s4	218	D	G.h2s4.03	Structure	Structure
G.h2s4	219	V	G.h2s4.04	Structure	Structure
G.h2s4	220	T	G.h2s4.05	Structure	Structure
G.S4	221	A	G.S4.01	Structure	Structure
G.S4	222	I	G.S4.02	Structure	Structure
G.S4	223	I	G.S4.03	Structure	Structure
G.S4	224	F	G.S4.04	Structure	Structure
G.S4	225	C	G.S4.05	Structure	Structure
G.S4	226	V	G.S4.06	Structure	Structure
G.S4	227	A	G.S4.07	Structure	AF2
G.s4h3	228	L	G.s4h3.01	Structure	Structure
G.s4h3	229	S	G.s4h3.02	Structure	AF2
G.s4h3	230	G	G.s4h3.03	Structure	AF2
G.s4h3	231	Y	G.s4h3.04	Structure	Structure
G.s4h3	232	D	G.s4h3.05	AF2	AF2
G.s4h3	233	Q	G.s4h3.06	AF2	AF2
G.s4h3	234	V	G.s4h3.07	AF2	AF2
G.s4h3	235	L	G.s4h3.08	AF2	AF2
G.s4h3	236	H	G.s4h3.09	AF2	AF2
G.s4h3	237	E	G.s4h3.10	AF2	AF2
G.s4h3	238	D	G.s4h3.11	AF2	AF2
G.s4h3	239	E	G.s4h3.12	AF2	AF2
G.s4h3	240	T	G.s4h3.13	AF2	AF2
G.s4h3	241	T	G.s4h3.14	AF2	AF2
G.s4h3	242	N	G.s4h3.15	AF2	AF2
G.H3	243	R	G.H3.01	AF2	AF2
G.H3	244	M	G.H3.02	Structure	Structure
G.H3	245	H	G.H3.03	Structure	AF2
G.H3	246	E	G.H3.04	Structure	Structure
G.H3	247	S	G.H3.05	Structure	Structure
G.H3	248	L	G.H3.06	Structure	Structure
G.H3	249	M	G.H3.07	Structure	AF2
G.H3	250	L	G.H3.08	Structure	Structure
G.H3	251	F	G.H3.09	Structure	Structure
G.H3	252	D	G.H3.10	Structure	Structure
G.H3	253	S	G.H3.11	Structure	Structure
G.H3	254	I	G.H3.12	Structure	Structure
G.H3	255	C	G.H3.13	Structure	Structure
G.H3	256	N	G.H3.14	Structure	Structure
G.H3	257	N	G.H3.15	Structure	Structure
G.H3	258	K	G.H3.16	Structure	Structure
G.H3	259	F	G.H3.17	Structure	Structure
G.H3	260	F	G.H3.18	Structure	Structure
G.h3s5	261	I	G.h3s5.01	Structure	Structure
G.h3s5	262	D	G.h3s5.02	Structure	AF2
G.h3s5	263	T	G.h3s5.03	Structure	Structure
G.S5	264	S	G.S5.01	Structure	Structure
G.S5	265	I	G.S5.02	Structure	AF2
G.S5	266	I	G.S5.03	Structure	Structure
G.S5	267	L	G.S5.04	Structure	Structure
G.S5	268	F	G.S5.05	Structure	Structure
G.S5	269	L	G.S5.06	Structure	Structure
G.S5	270	N	G.S5.07	Structure	Structure
G.s5hg	271	K	G.s5hg.01	Structure	Structure
G.HG	272	K	G.HG.01	Structure	AF2
G.HG	273	D	G.HG.02	Structure	Structure
G.HG	274	L	G.HG.03	Structure	Structure
G.HG	275	F	G.HG.04	Structure	Structure
G.HG	276	G	G.HG.05	Structure	Structure
G.HG	277	E	G.HG.06	Structure	Structure
G.HG	278	K	G.HG.07	Structure	Structure
G.HG	279	I	G.HG.08	Structure	Structure
G.HG	280	K	G.HG.09	Structure	AF2
G.HG	281	K	G.HG.12	Structure	AF2
G.HG	282	S	G.HG.13	Structure	Structure
G.HG	283	P	G.HG.14	Structure	Structure
G.HG	284	L	G.HG.15	Structure	AF2
G.HG	285	T	G.HG.16	Structure	Structure
G.HG	286	I	G.HG.17	Structure	Structure
G.hgh4	287	C	G.hgh4.01	Structure	Structure
G.hgh4	288	F	G.hgh4.02	Structure	Structure
G.hgh4	289	P	G.hgh4.03	Structure	Structure
G.hgh4	290	E	G.hgh4.04	Structure	Structure
G.hgh4	291	Y	G.hgh4.05	Structure	Structure
G.hgh4	292	T	G.hgh4.06	Structure	Structure
G.hgh4	293	G	G.hgh4.07	Structure	Structure
G.hgh4	294	P	G.hgh4.08	Structure	Structure
G.H4	295	N	G.H4.01	Structure	Structure
G.H4	296	T	G.H4.02	Structure	Structure
G.H4	297	Y	G.H4.03	Structure	Structure
G.H4	298	E	G.H4.04	Structure	AF2
G.H4	299	D	G.H4.05	Structure	Structure
G.H4	300	A	G.H4.06	Structure	Structure
G.H4	301	A	G.H4.07	Structure	Structure
G.H4	302	A	G.H4.08	Structure	Structure
G.H4	303	Y	G.H4.10	Structure	Structure
G.H4	304	I	G.H4.11	Structure	Structure
G.H4	305	Q	G.H4.12	Structure	Structure
G.H4	306	A	G.H4.13	Structure	Structure
G.H4	307	Q	G.H4.14	Structure	Structure
G.H4	308	F	G.H4.15	Structure	Structure
G.H4	309	E	G.H4.16	Structure	Structure
G.H4	310	S	G.H4.17	Structure	Structure
G.h4s6	311	K	G.h4s6.01	Structure	Structure
G.h4s6	312	N	G.h4s6.02	Structure	Structure
G.h4s6	313	R	G.h4s6.03	Structure	Structure
G.h4s6	314	S	G.h4s6.08	Structure	AF2
G.h4s6	315	P	G.h4s6.09	Structure	Structure
G.h4s6	316	N	G.h4s6.10	Structure	AF2
G.h4s6	317	K	G.h4s6.11	Structure	Structure
G.h4s6	318	E	G.h4s6.12	Structure	Structure
G.S6	319	I	G.S6.01	Structure	Structure
G.S6	320	Y	G.S6.02	Structure	Structure
G.S6	321	C	G.S6.03	Structure	Structure
G.S6	322	H	G.S6.04	Structure	Structure
G.S6	323	M	G.S6.05	Structure	Structure
G.s6h5	324	T	G.s6h5.01	Structure	AF2
G.s6h5	325	C	G.s6h5.02	Structure	AF2
G.s6h5	326	A	G.s6h5.03	Structure	Structure
G.s6h5	327	T	G.s6h5.04	Structure	AF2
G.s6h5	328	D	G.s6h5.05	Structure	AF2
G.H5	329	T	G.H5.01	Structure	AF2
G.H5	330	N	G.H5.02	Structure	Structure
G.H5	331	N	G.H5.03	Structure	Structure
G.H5	332	I	G.H5.04	Structure	AF2
G.H5	333	Q	G.H5.05	Structure	Structure
G.H5	334	V	G.H5.06	Structure	Structure
G.H5	335	V	G.H5.07	Structure	AF2
G.H5	336	F	G.H5.08	Structure	Structure
G.H5	337	D	G.H5.09	Structure	Structure
G.H5	338	A	G.H5.10	Structure	Structure
G.H5	339	V	G.H5.11	Structure	Structure
G.H5	340	T	G.H5.12	Structure	Structure
G.H5	341	D	G.H5.13	Structure	Structure
G.H5	342	I	G.H5.14	Structure	Structure
G.H5	343	I	G.H5.15	Structure	Structure
G.H5	344	I	G.H5.16	Structure	Structure
G.H5	345	A	G.H5.17	Structure	Structure
G.H5	346	N	G.H5.18	Structure	Structure
G.H5	347	N	G.H5.19	Structure	Structure
G.H5	348	L	G.H5.20	Structure	Structure
G.H5	349	R	G.H5.21	Structure	Structure
G.H5	350	G	G.H5.22	Structure	Structure
G.H5	351	C	G.H5.23	Structure	Structure
G.H5	352	G	G.H5.24	Structure	Structure
G.H5	353	L	G.H5.25	Structure	Structure
G.H5	354	Y	G.H5.26	Structure	Structure

REFINED GPCR RESIDUES

Residue backbones - 276 from structure (60.3%), 182 from model (39.7%)
Residue sidechains - 236 from structure (51.5%), 222 from model (48.5%)

Showing 1 to 458 of 458 entries

Search:

Segment	Seq.num.	AA	GPCRdb#	Backbone from	Sidechain from

N-term	1	M	-	AF2	AF2
N-term	2	A	-	AF2	AF2
N-term	3	S	-	AF2	AF2
N-term	4	F	-	AF2	AF2
N-term	5	S	-	AF2	AF2
N-term	6	A	-	AF2	AF2
N-term	7	E	-	AF2	AF2
N-term	8	T	-	AF2	AF2
N-term	9	N	-	AF2	AF2
N-term	10	S	-	AF2	AF2
N-term	11	T	-	AF2	AF2
N-term	12	D	-	AF2	AF2
N-term	13	L	-	AF2	AF2
N-term	14	L	-	AF2	AF2
N-term	15	S	-	AF2	AF2
N-term	16	Q	-	AF2	AF2
N-term	17	P	-	AF2	AF2
N-term	18	W	-	AF2	AF2
N-term	19	N	-	AF2	AF2
TM1	20	E	1.29x29	Structure	AF2
TM1	21	P	1.30x30	Structure	Structure
TM1	22	P	1.31x31	Structure	Structure
TM1	23	V	1.32x32	Structure	Structure
TM1	24	I	1.33x33	Structure	Structure
TM1	25	L	1.34x34	Structure	Structure
TM1	26	S	1.35x35	Structure	Structure
TM1	27	M	1.36x36	Structure	Structure
TM1	28	V	1.37x37	Structure	Structure
TM1	29	I	1.38x38	Structure	Structure
TM1	30	L	1.39x39	Structure	Structure
TM1	31	S	1.40x40	Structure	Structure
TM1	32	L	1.41x41	Structure	Structure
TM1	33	T	1.42x42	Structure	Structure
TM1	34	F	1.43x43	Structure	Structure
TM1	35	L	1.44x44	Structure	Structure
TM1	36	L	1.45x45	Structure	Structure
TM1	37	G	1.46x46	Structure	Structure
TM1	38	L	1.47x47	Structure	Structure
TM1	39	P	1.48x48	Structure	Structure
TM1	40	G	1.49x49	Structure	Structure
TM1	41	N	1.50x50	Structure	Structure
TM1	42	G	1.51x51	Structure	Structure
TM1	43	L	1.52x52	Structure	Structure
TM1	44	V	1.53x53	Structure	Structure
TM1	45	L	1.54x54	Structure	Structure
TM1	46	W	1.55x55	Structure	AF2
TM1	47	V	1.56x56	Structure	Structure
TM1	48	A	1.57x57	Structure	Structure
TM1	49	G	1.58x58	Structure	Structure
TM1	50	L	1.59x59	Structure	Structure
TM1	51	K	1.60x60	Structure	AF2
ICL1	52	M	-	Structure	AF2
ICL1	53	Q	-	Structure	Structure
ICL1	54	R	-	Structure	AF2
TM2	55	T	2.37x37	Structure	Structure
TM2	56	V	2.38x38	Structure	Structure
TM2	57	N	2.39x39	Structure	Structure
TM2	58	T	2.40x40	Structure	AF2
TM2	59	I	2.41x41	Structure	Structure
TM2	60	W	2.42x42	Structure	Structure
TM2	61	F	2.43x43	Structure	Structure
TM2	62	L	2.44x44	Structure	Structure
TM2	63	H	2.45x45	Structure	Structure
TM2	64	L	2.46x46	Structure	Structure
TM2	65	T	2.47x47	Structure	Structure
TM2	66	L	2.48x48	Structure	Structure
TM2	67	A	2.49x49	Structure	Structure
TM2	68	D	2.50x50	Structure	Structure
TM2	69	L	2.51x51	Structure	Structure
TM2	70	L	2.52x52	Structure	Structure
TM2	71	C	2.53x53	Structure	Structure
TM2	72	C	2.54x54	Structure	Structure
TM2	73	L	2.55x55	Structure	Structure
TM2	74	S	2.56x56	Structure	Structure
TM2	75	L	2.57x57	Structure	Structure
TM2	76	P	2.58x58	Structure	Structure
TM2	77	F	2.59x59	Structure	Structure
TM2	78	S	2.60x60	Structure	Structure
TM2	79	L	2.61x61	Structure	Structure
TM2	80	A	2.62x62	Structure	Structure
TM2	81	H	2.63x63	Structure	Structure
TM2	82	L	2.64x64	Structure	AF2
TM2	83	A	2.65x65	Structure	Structure
TM2	84	L	2.66x66	Structure	Structure
TM2	85	Q	2.67x67	Structure	AF2
ECL1	86	G	-	Structure	Structure
ECL1	87	Q	23.49x49	Structure	AF2
ECL1	88	W	23.50x50	Structure	Structure
ECL1	89	P	23.51x51	Structure	Structure
ECL1	90	Y	23.52x52	Structure	Structure
TM3	91	G	3.21x21	Structure	Structure
TM3	92	R	3.22x22	Structure	Structure
TM3	93	F	3.23x23	Structure	Structure
TM3	94	L	3.24x24	Structure	AF2
TM3	95	C	3.25x25	Structure	Structure
TM3	96	K	3.26x26	Structure	Structure
TM3	97	L	3.27x27	Structure	AF2
TM3	98	I	3.28x28	Structure	AF2
TM3	99	P	3.29x29	Structure	Structure
TM3	100	S	3.30x30	Structure	Structure
TM3	101	I	3.31x31	Structure	AF2
TM3	102	I	3.32x32	Structure	Structure
TM3	103	V	3.33x33	Structure	Structure
TM3	104	L	3.34x34	Structure	Structure
TM3	105	N	3.35x35	Structure	AF2
TM3	106	M	3.36x36	Structure	Structure
TM3	107	F	3.37x37	Structure	Structure
TM3	108	A	3.38x38	Structure	Structure
TM3	109	S	3.39x39	Structure	Structure
TM3	110	V	3.40x40	Structure	Structure
TM3	111	F	3.41x41	Structure	Structure
TM3	112	L	3.42x42	Structure	Structure
TM3	113	L	3.43x43	Structure	Structure
TM3	114	T	3.44x44	Structure	Structure
TM3	115	A	3.45x45	Structure	Structure
TM3	116	I	3.46x46	Structure	Structure
TM3	117	S	3.47x47	Structure	Structure
TM3	118	L	3.48x48	Structure	Structure
TM3	119	D	3.49x49	Structure	Structure
TM3	120	R	3.50x50	Structure	Structure
TM3	121	C	3.51x51	Structure	Structure
TM3	122	L	3.52x52	Structure	Structure
TM3	123	V	3.53x53	Structure	Structure
TM3	124	V	3.54x54	Structure	Structure
TM3	125	F	3.55x55	Structure	Structure
TM3	126	K	3.56x56	Structure	Structure
ICL2	127	P	34.50x50	Structure	Structure
ICL2	128	I	34.51x51	Structure	AF2
ICL2	129	W	34.52x52	Structure	Structure
ICL2	130	C	34.53x53	Structure	Structure
ICL2	131	Q	34.54x54	Structure	Structure
ICL2	132	N	34.55x55	Structure	Structure
ICL2	133	H	34.56x56	Structure	Structure
ICL2	134	R	34.57x57	Structure	Structure
TM4	135	N	4.38x38	Structure	Structure
TM4	136	V	4.39x39	Structure	Structure
TM4	137	G	4.40x40	Structure	Structure
TM4	138	M	4.41x41	Structure	Structure
TM4	139	A	4.42x42	Structure	Structure
TM4	140	C	4.43x43	Structure	Structure
TM4	141	S	4.44x44	Structure	Structure
TM4	142	I	4.45x45	Structure	Structure
TM4	143	C	4.46x46	Structure	Structure
TM4	144	G	4.47x47	Structure	Structure
TM4	145	C	4.48x48	Structure	Structure
TM4	146	I	4.49x49	Structure	Structure
TM4	147	W	4.50x50	Structure	Structure
TM4	148	V	4.51x51	Structure	Structure
TM4	149	V	4.52x52	Structure	Structure
TM4	150	A	4.53x53	Structure	Structure
TM4	151	F	4.54x54	Structure	Structure
TM4	152	V	4.55x55	Structure	Structure
TM4	153	M	4.56x56	Structure	AF2
TM4	154	C	4.57x57	Structure	Structure
TM4	155	I	4.58x59	Structure	AF2
TM4	156	P	4.59x60	Structure	Structure
TM4	157	V	4.60x61	Structure	Structure
TM4	158	F	4.61x62	Structure	AF2
TM4	159	V	4.62x63	Structure	Structure
TM4	160	Y	4.63x64	Structure	Structure
TM4	161	R	4.64x65	Structure	Structure
ECL2	162	E	-	Structure	Structure
ECL2	163	I	-	Structure	Structure
ECL2	164	F	-	Structure	Structure
ECL2	165	T	-	Structure	Structure
ECL2	166	T	-	Structure	AF2
ECL2	167	D	-	Structure	AF2
ECL2	168	N	-	Structure	AF2
ECL2	169	H	-	Structure	AF2
ECL2	170	N	-	Structure	AF2
ECL2	171	R	-	Structure	AF2
ECL2	172	C	45.50x50	Structure	Structure
ECL2	173	G	45.51x51	Structure	Structure
ECL2	174	Y	45.52x52	Structure	Structure
ECL2	175	K	-	Structure	AF2
ECL2	176	F	-	AF2	AF2
ECL2	177	G	-	AF2	AF2
ECL2	178	L	-	AF2	AF2
ECL2	179	S	-	AF2	AF2
ECL2	180	S	-	AF2	AF2
ECL2	181	S	-	AF2	AF2
ECL2	182	L	-	AF2	AF2
ECL2	183	D	-	AF2	AF2
ECL2	184	Y	-	AF2	AF2
ECL2	185	P	-	AF2	AF2
ECL2	186	D	-	AF2	AF2
ECL2	187	F	-	AF2	AF2
ECL2	188	Y	-	AF2	AF2
ECL2	189	G	-	AF2	AF2
ECL2	190	D	-	AF2	AF2
ECL2	191	P	-	AF2	AF2
ECL2	192	L	-	AF2	AF2
ECL2	193	E	-	AF2	AF2
ECL2	194	N	-	AF2	AF2
ECL2	195	R	-	AF2	AF2
ECL2	196	S	-	AF2	AF2
ECL2	197	L	-	AF2	AF2
ECL2	198	E	-	AF2	AF2
ECL2	199	N	-	AF2	AF2
ECL2	200	I	-	AF2	AF2
ECL2	201	V	-	AF2	AF2
ECL2	202	Q	-	AF2	AF2
ECL2	203	P	-	AF2	AF2
ECL2	204	P	-	AF2	AF2
ECL2	205	G	-	AF2	AF2
ECL2	206	E	-	AF2	AF2
ECL2	207	M	-	AF2	AF2
ECL2	208	N	-	AF2	AF2
ECL2	209	D	-	AF2	AF2
ECL2	210	R	-	AF2	AF2
ECL2	211	L	-	AF2	AF2
ECL2	212	D	-	AF2	AF2
ECL2	213	P	-	AF2	AF2
ECL2	214	S	-	AF2	AF2
ECL2	215	S	-	AF2	AF2
ECL2	216	F	-	AF2	AF2
ECL2	217	Q	-	AF2	AF2
ECL2	218	T	-	AF2	AF2
ECL2	219	N	-	AF2	AF2
ECL2	220	D	-	AF2	AF2
ECL2	221	H	-	AF2	AF2
ECL2	222	P	-	AF2	AF2
ECL2	223	W	-	AF2	AF2
ECL2	224	T	-	AF2	AF2
ECL2	225	V	-	AF2	AF2
ECL2	226	P	-	AF2	AF2
ECL2	227	T	-	AF2	AF2
ECL2	228	V	-	AF2	AF2
ECL2	229	F	-	AF2	AF2
ECL2	230	Q	-	AF2	AF2
ECL2	231	P	-	AF2	AF2
ECL2	232	Q	-	AF2	AF2
ECL2	233	T	-	AF2	AF2
ECL2	234	F	-	AF2	AF2
ECL2	235	Q	-	AF2	AF2
ECL2	236	R	-	AF2	AF2
ECL2	237	P	-	AF2	AF2
ECL2	238	S	-	AF2	AF2
ECL2	239	A	-	AF2	AF2
ECL2	240	D	-	AF2	AF2
ECL2	241	S	-	AF2	AF2
ECL2	242	L	-	AF2	AF2
ECL2	243	P	-	AF2	AF2
ECL2	244	R	-	AF2	AF2
ECL2	245	G	-	AF2	AF2
ECL2	246	S	-	AF2	AF2
ECL2	247	A	-	AF2	AF2
ECL2	248	R	-	AF2	AF2
ECL2	249	L	-	AF2	AF2
ECL2	250	T	-	AF2	AF2
ECL2	251	S	-	AF2	AF2
ECL2	252	Q	-	AF2	AF2
ECL2	253	N	-	AF2	AF2
ECL2	254	L	-	AF2	AF2
ECL2	255	Y	-	AF2	AF2
ECL2	256	S	-	AF2	AF2
ECL2	257	N	-	AF2	AF2
ECL2	258	V	-	AF2	AF2
ECL2	259	F	-	AF2	AF2
ECL2	260	K	-	AF2	AF2
ECL2	261	P	-	AF2	AF2
ECL2	262	A	-	AF2	AF2
ECL2	263	D	-	AF2	AF2
ECL2	264	V	-	AF2	AF2
ECL2	265	V	-	AF2	AF2
ECL2	266	S	-	AF2	AF2
ECL2	267	P	-	AF2	AF2
ECL2	268	K	-	AF2	AF2
ECL2	269	I	-	AF2	AF2
ECL2	270	P	-	AF2	AF2
ECL2	271	S	-	AF2	AF2
ECL2	272	G	-	AF2	AF2
ECL2	273	F	-	AF2	AF2
ECL2	274	P	-	AF2	AF2
ECL2	275	I	-	AF2	AF2
ECL2	276	E	-	AF2	AF2
ECL2	277	D	-	AF2	AF2
ECL2	278	H	-	AF2	AF2
ECL2	279	E	-	AF2	AF2
ECL2	280	T	-	AF2	AF2
ECL2	281	S	-	AF2	AF2
ECL2	282	P	-	AF2	AF2
ECL2	283	L	-	AF2	AF2
ECL2	284	D	-	AF2	AF2
ECL2	285	N	-	AF2	AF2
ECL2	286	S	-	AF2	AF2
ECL2	287	D	-	AF2	AF2
ECL2	288	A	-	AF2	AF2
ECL2	289	F	-	AF2	AF2
ECL2	290	L	-	AF2	AF2
ECL2	291	S	-	AF2	AF2
ECL2	292	T	-	AF2	AF2
ECL2	293	H	-	AF2	AF2
ECL2	294	L	-	AF2	AF2
ECL2	295	K	-	AF2	AF2
ECL2	296	L	-	AF2	AF2
ECL2	297	F	-	AF2	AF2
ECL2	298	P	-	AF2	AF2
ECL2	299	S	-	AF2	AF2
ECL2	300	A	-	AF2	AF2
ECL2	301	S	-	AF2	AF2
ECL2	302	S	-	AF2	AF2
ECL2	303	N	-	AF2	AF2
ECL2	304	S	-	AF2	AF2
ECL2	305	F	-	AF2	AF2
ECL2	306	Y	-	AF2	AF2
ECL2	307	E	-	AF2	AF2
ECL2	308	S	-	AF2	AF2
ECL2	309	E	-	AF2	AF2
ECL2	310	L	-	AF2	AF2
ECL2	311	P	-	AF2	AF2
ECL2	312	Q	-	AF2	AF2
ECL2	313	G	-	AF2	AF2
ECL2	314	F	-	AF2	AF2
ECL2	315	Q	-	AF2	AF2
ECL2	316	D	-	AF2	AF2
ECL2	317	Y	-	AF2	AF2
ECL2	318	Y	-	AF2	AF2
ECL2	319	N	-	AF2	AF2
ECL2	320	L	-	AF2	AF2
ECL2	321	G	-	AF2	AF2
ECL2	322	Q	-	AF2	AF2
ECL2	323	F	-	AF2	AF2
ECL2	324	T	-	AF2	AF2
ECL2	325	D	-	AF2	AF2
ECL2	326	D	-	AF2	AF2
ECL2	327	D	-	AF2	AF2
ECL2	328	Q	-	AF2	AF2
TM5	329	V	5.31x32	AF2	AF2
TM5	330	P	5.32x33	AF2	AF2
TM5	331	T	5.33x34	Structure	Structure
TM5	332	P	5.34x35	Structure	Structure
TM5	333	L	5.35x36	Structure	Structure
TM5	334	V	5.36x37	Structure	Structure
TM5	335	A	5.37x38	Structure	Structure
TM5	336	I	5.38x39	Structure	Structure
TM5	337	T	5.39x40	Structure	Structure
TM5	338	I	5.40x41	Structure	Structure
TM5	339	T	5.41x42	Structure	AF2
TM5	340	R	5.42x43	Structure	Structure
TM5	341	L	5.43x44	Structure	Structure
TM5	342	V	5.44x45	Structure	Structure
TM5	343	V	5.45x46	Structure	Structure
TM5	344	G	5.46x461	Structure	Structure
TM5	345	F	5.47x47	Structure	Structure
TM5	346	L	5.48x48	Structure	Structure
TM5	347	L	5.49x49	Structure	Structure
TM5	348	P	5.50x50	Structure	Structure
TM5	349	S	5.51x51	Structure	Structure
TM5	350	V	5.52x52	Structure	Structure
TM5	351	I	5.53x53	Structure	Structure
TM5	352	M	5.54x54	Structure	Structure
TM5	353	I	5.55x55	Structure	Structure
TM5	354	A	5.56x56	Structure	Structure
TM5	355	C	5.57x57	Structure	Structure
TM5	356	Y	5.58x58	Structure	Structure
TM5	357	S	5.59x59	Structure	Structure
TM5	358	F	5.60x60	Structure	Structure
TM5	359	I	5.61x61	Structure	Structure
TM5	360	V	5.62x62	Structure	Structure
TM5	361	F	5.63x63	Structure	Structure
TM5	362	R	5.64x64	Structure	Structure
TM5	363	M	5.65x65	Structure	AF2
TM5	364	Q	5.66x66	Structure	Structure
TM5	365	R	5.67x67	Structure	Structure
ICL3	366	G	-	Structure	Structure
ICL3	367	R	-	Structure	AF2
ICL3	368	F	-	Structure	Structure
ICL3	369	A	-	Structure	Structure
ICL3	370	K	-	Structure	Structure
ICL3	371	S	-	Structure	Structure
ICL3	372	Q	-	Structure	Structure
TM6	373	S	6.31x31	Structure	Structure
TM6	374	K	6.32x32	Structure	Structure
TM6	375	T	6.33x33	Structure	Structure
TM6	376	F	6.34x34	Structure	Structure
TM6	377	R	6.35x35	Structure	AF2
TM6	378	V	6.36x36	Structure	Structure
TM6	379	A	6.37x37	Structure	Structure
TM6	380	V	6.38x38	Structure	Structure
TM6	381	V	6.39x39	Structure	Structure
TM6	382	V	6.40x40	Structure	Structure
TM6	383	V	6.41x41	Structure	Structure
TM6	384	A	6.42x42	Structure	Structure
TM6	385	V	6.43x43	Structure	Structure
TM6	386	F	6.44x44	Structure	Structure
TM6	387	L	6.45x45	Structure	Structure
TM6	388	V	6.46x46	Structure	Structure
TM6	389	C	6.47x47	Structure	Structure
TM6	390	W	6.48x48	Structure	Structure
TM6	391	T	6.49x49	Structure	Structure
TM6	392	P	6.50x50	Structure	Structure
TM6	393	Y	6.51x51	Structure	Structure
TM6	394	H	6.52x52	Structure	Structure
TM6	395	I	6.53x53	Structure	Structure
TM6	396	F	6.54x54	Structure	Structure
TM6	397	G	6.55x55	Structure	Structure
TM6	398	V	6.56x56	Structure	Structure
TM6	399	L	6.57x57	Structure	Structure
TM6	400	S	6.58x58	Structure	Structure
TM6	401	L	6.59x59	Structure	Structure
TM6	402	L	6.60x60	Structure	AF2
TM6	403	T	6.61x61	Structure	AF2
ECL3	404	D	-	Structure	Structure
ECL3	405	P	-	Structure	Structure
ECL3	406	E	-	Structure	AF2
TM7	407	T	7.25x24	Structure	Structure
TM7	408	P	7.26x25	Structure	Structure
TM7	409	L	7.27x26	Structure	AF2
TM7	410	G	7.28x27	Structure	Structure
TM7	411	K	7.29x28	Structure	AF2
TM7	412	T	7.30x29	Structure	Structure
TM7	413	L	7.31x30	Structure	Structure
TM7	414	M	7.32x31	Structure	Structure
TM7	415	S	7.33x32	Structure	Structure
TM7	416	W	7.34x33	Structure	Structure
TM7	417	D	7.35x34	Structure	Structure
TM7	418	H	7.36x35	Structure	Structure
TM7	419	V	7.37x36	Structure	Structure
TM7	420	C	7.38x37	Structure	Structure
TM7	421	I	7.39x38	Structure	Structure
TM7	422	A	7.40x39	Structure	Structure
TM7	423	L	7.41x40	Structure	Structure
TM7	424	A	7.42x41	Structure	Structure
TM7	425	S	7.43x42	Structure	Structure
TM7	426	A	7.44x43	Structure	Structure
TM7	427	N	7.45x45	Structure	Structure
TM7	428	S	7.46x46	Structure	Structure
TM7	429	C	7.47x47	Structure	Structure
TM7	430	F	7.48x48	Structure	Structure
TM7	431	N	7.49x49	Structure	Structure
TM7	432	P	7.50x50	Structure	Structure
TM7	433	F	7.51x51	Structure	Structure
TM7	434	L	7.52x52	Structure	Structure
TM7	435	Y	7.53x53	Structure	Structure
TM7	436	A	7.54x54	Structure	Structure
TM7	437	L	7.55x55	Structure	Structure
TM7	438	L	7.56x56	Structure	Structure
H8	439	G	8.47x47	Structure	Structure
H8	440	K	8.48x48	Structure	AF2
H8	441	D	8.49x49	Structure	AF2
H8	442	F	8.50x50	Structure	AF2
H8	443	R	8.51x51	Structure	Structure
H8	444	K	8.52x52	Structure	AF2
H8	445	K	8.53x53	Structure	Structure
H8	446	A	8.54x54	Structure	Structure
H8	447	R	8.55x55	Structure	AF2
H8	448	Q	8.56x56	Structure	AF2
C-term	449	S	-	Structure	Structure
C-term	450	I	-	Structure	Structure
C-term	451	Q	-	AF2	AF2
C-term	452	G	-	AF2	AF2
C-term	453	I	-	AF2	AF2
C-term	454	L	-	AF2	AF2
C-term	455	E	-	AF2	AF2
C-term	456	A	-	AF2	AF2
C-term	457	A	-	AF2	AF2
C-term	458	F	-	AF2	AF2

GPCR - G protein interface interactions

The biflare plot is a modified version of a flareplot, where lines are drawn between an inner concentric circle (Gα residues) and an outer concentric circle (GPCR residues) depicting the interface interactions.
Different interaction types are shown with different line types (aromatic - solid, hydrophobic - dashed, ionic - long dashed, polar - dotted, Van der Waals - dash-dot).
The interactive features include filtering on interaction type, segments, residues and backbone or sidechain interactions.

Interaction cut-off:

Residue numbering:

GPCR-G protein backbone (bb) or sidechain (sc):

bb-bb

bb-sc

sc-sc

sc-bb

Structures

Sequence Color

Gα, Gβ, Gγ, GPCR
Interaction cut-off: strict (stick), loose (line)

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Interaction type	GPCR Segment	AA	Number	Generic number	Gα segment	AA	Number	Generic number

Interaction type	GPCR Segment	AA	Number	Generic number	Gα segment	AA	Number	Generic number

Aromatic	TM6	K	374	6x32	G.H5	Y	354	G.H5.26
Aromatic	ICL3	R	367	-	G.S6	Y	320	G.S6.02
Hydrophobic	ICL2	Q	131	34x54	G.S1	V	34	G.S1.02
Hydrophobic	ICL2	Q	131	34x54	G.hns1	K	32	G.hns1.03
Hydrophobic	ICL3	F	368	-	G.H5	Y	354	G.H5.26
Hydrophobic	TM3	V	124	3x54	G.H5	I	344	G.H5.16
Hydrophobic	TM5	R	362	5x64	G.H5	I	344	G.H5.16
Hydrophobic	ICL2	I	128	34x51	G.H5	F	336	G.H5.08
Hydrophobic	ICL2	I	128	34x51	G.S3	L	195	G.S3.01
Hydrophobic	TM6	T	375	6x33	G.H5	L	353	G.H5.25
Hydrophobic	TM3	V	124	3x54	G.H5	L	348	G.H5.20
Hydrophobic	ICL2	N	132	34x55	G.hns1	K	32	G.hns1.03
Hydrophobic	H8	G	439	8x47	G.H5	G	352	G.H5.24
Hydrophobic	ICL2	I	128	34x51	G.H5	T	340	G.H5.12
Hydrophobic	ICL3	S	371	-	G.H5	Y	354	G.H5.26
Hydrophobic	TM3	V	123	3x53	G.H5	N	347	G.H5.19
Hydrophobic	TM6	V	378	6x36	G.H5	L	353	G.H5.25
Hydrophobic	TM5	I	359	5x61	G.H5	L	348	G.H5.20
Hydrophobic	ICL3	R	367	-	G.S6	I	319	G.S6.01
Hydrophobic	ICL3	F	368	-	G.H5	L	348	G.H5.20
Hydrophobic	ICL2	Q	131	34x54	G.S3	L	195	G.S3.01
Hydrophobic	TM5	I	359	5x61	G.H5	L	353	G.H5.25
Hydrophobic	TM3	R	120	3x50	G.H5	L	353	G.H5.25
Hydrophobic	TM2	N	57	2x39	G.H5	G	350	G.H5.22
Hydrophobic	ICL3	F	368	-	G.H5	I	344	G.H5.16
Hydrophobic	TM5	Y	356	5x58	G.H5	L	353	G.H5.25
Hydrophobic	ICL2	P	127	34x50	G.H5	I	343	G.H5.15
Hydrophobic	ICL3	R	367	-	G.h4s6	E	318	G.h4s6.12
Hydrophobic	ICL3	F	368	-	G.H5	A	345	G.H5.17
Hydrophobic	TM5	M	363	5x65	G.H5	L	348	G.H5.20
Hydrophobic	ICL3	R	367	-	G.S6	Y	320	G.S6.02
Hydrophobic	ICL2	P	127	34x50	G.H5	T	340	G.H5.12
Hydrophobic	ICL2	P	127	34x50	G.H5	I	344	G.H5.16
Hydrophobic	ICL2	Q	131	34x54	G.H5	I	343	G.H5.15
Hydrophobic	ICL3	F	368	-	G.H5	D	341	G.H5.13
Hydrophobic	ICL2	I	128	34x51	G.s2s3	N	194	G.s2s3.02
Hydrophobic	TM3	R	120	3x50	G.H5	C	351	G.H5.23
Hydrophobic	ICL3	R	367	-	G.H5	D	341	G.H5.13
Ionic	ICL3	R	367	-	G.H5	D	341	G.H5.13
Polar	ICL2	Q	131	34x54	G.hns1	K	32	G.hns1.03
Polar	ICL3	K	370	-	G.H5	Y	354	G.H5.26
Polar	TM6	T	375	6x33	G.H5	L	353	G.H5.25
Polar	ICL2	N	132	34x55	G.s2s3	N	194	G.s2s3.02
Polar	ICL3	R	367	-	G.S6	I	319	G.S6.01
Polar	ICL2	Q	131	34x54	G.hns1	A	31	G.hns1.02
Polar	ICL3	R	367	-	G.S6	Y	320	G.S6.02
Polar	ICL3	K	370	-	G.h4s6	P	315	G.h4s6.09
Polar	TM3	R	120	3x50	G.H5	C	351	G.H5.23
Van-der-waals	ICL2	Q	131	34x54	G.S1	V	34	G.S1.02
Van-der-waals	ICL2	Q	131	34x54	G.hns1	K	32	G.hns1.03
Van-der-waals	TM3	V	124	3x54	G.H5	I	344	G.H5.16
Van-der-waals	ICL2	I	128	34x51	G.H5	F	336	G.H5.08
Van-der-waals	TM3	V	124	3x54	G.H5	L	348	G.H5.20
Van-der-waals	ICL2	N	132	34x55	G.hns1	K	32	G.hns1.03
Van-der-waals	ICL2	I	128	34x51	G.H5	T	340	G.H5.12
Van-der-waals	TM3	V	123	3x53	G.H5	N	347	G.H5.19
Van-der-waals	ICL2	N	132	34x55	G.s2s3	N	194	G.s2s3.02
Van-der-waals	TM6	V	378	6x36	G.H5	L	353	G.H5.25
Van-der-waals	ICL3	R	367	-	G.S6	I	319	G.S6.01
Van-der-waals	TM5	I	359	5x61	G.H5	L	353	G.H5.25
Van-der-waals	ICL3	F	368	-	G.H5	I	344	G.H5.16
Van-der-waals	ICL3	R	367	-	G.h4s6	E	318	G.h4s6.12
Van-der-waals	TM5	M	363	5x65	G.H5	L	348	G.H5.20
Van-der-waals	ICL3	R	367	-	G.S6	Y	320	G.S6.02
Van-der-waals	ICL3	K	370	-	G.h4s6	P	315	G.h4s6.09
Van-der-waals	ICL2	P	127	34x50	G.H5	I	344	G.H5.16
Van-der-waals	TM3	R	120	3x50	G.H5	C	351	G.H5.23

Showing 1 to 67 of 67 entries

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Main reference

Refined structure (8J6D) of Go - C3a receptor Download Full

GPCR CLASS (FAMILY)

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G PROTEIN FAMILY

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REFINED G PROTEIN RESIDUES

REFINED GPCR RESIDUES

GPCR - G protein interface interactions

Structures

Refined structure (8J6D) of G_o - C3a receptor

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