PDB
6JOD
Resolution
3.2 Å
Released
Jan. 15, 2020
Receptor
AT2
Class
A
Species
Homo sapiens
Ligand
angiotensin II (Human)
Function
Agonist
Reference
10.1016/J.STR.2019.12.003

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
angiotensin II (Human) W100 2.60x60 TM2 hydrophobic
angiotensin II (Human) Y103 2.63x63 TM2 Van der Waals
angiotensin II (Human) Y103 2.63x63 TM2 polar (hydrogen bond)
angiotensin II (Human) Y104 2.64x64 TM2 polar (hydrogen bond)
angiotensin II (Human) Y108 ECL1 Van der Waals
angiotensin II (Human) Y108 ECL1 hydrophobic
angiotensin II (Human) L124 3.32x32 TM3 hydrophobic
angiotensin II (Human) L124 3.32x32 TM3 Van der Waals
angiotensin II (Human) T125 3.33x33 TM3 Van der Waals
angiotensin II (Human) M128 3.36x36 TM3 Van der Waals
angiotensin II (Human) M128 3.36x36 TM3 hydrophobic
angiotensin II (Human) R182 4.64x65 TM4 polar (charge-assisted hydrogen bond)
angiotensin II (Human) C195 45.50x50 ECL2 Van der Waals
angiotensin II (Human) I196 45.51x51 ECL2 Van der Waals
angiotensin II (Human) I196 45.51x51 ECL2 hydrophobic
angiotensin II (Human) M197 45.52x52 ECL2 Van der Waals
angiotensin II (Human) M197 45.52x52 ECL2 polar (hydrogen bond with backbone)
angiotensin II (Human) Y204 5.31x32 TM5 polar (hydrogen bond)
angiotensin II (Human) Y204 5.31x32 TM5 Van der Waals
angiotensin II (Human) K215 5.42x43 TM5 polar (charge-assisted hydrogen bond)
angiotensin II (Human) W269 6.48x48 TM6 hydrophobic
angiotensin II (Human) W269 6.48x48 TM6 Van der Waals
angiotensin II (Human) F272 6.51x51 TM6 hydrophobic
angiotensin II (Human) F272 6.51x51 TM6 Van der Waals
angiotensin II (Human) D279 6.58x58 TM6 polar (charge-assisted hydrogen bond)
angiotensin II (Human) W283 6.62x62 TM6 Van der Waals
angiotensin II (Human) W283 6.62x62 TM6 hydrophobic
angiotensin II (Human) I293 7.28x27 TM7 Van der Waals
angiotensin II (Human) D297 7.32x31 TM7 Van der Waals
angiotensin II (Human) L300 7.35x34 TM7 Van der Waals
angiotensin II (Human) L300 7.35x34 TM7 hydrophobic
angiotensin II (Human) P301 7.36x35 TM7 Van der Waals
angiotensin II (Human) I304 7.39x38 TM7 Van der Waals
angiotensin II (Human) I304 7.39x38 TM7 hydrophobic

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 K G P K K ICL1ECL1 Y D W L F ECL1ICL2 P F L S Q R R ICL2ECL2 D V R T I E Y L G V N A C I M A F P P E ECL2ICL3 N S Y ICL3ECL3 V I N ECL3N-term M K G N S T L A T T S K N I T S G L H F G L V N I S G N N E S T L N C S Q K P S D K H L N-termC-term I T W L Q G K R E S M S C R K S S S L R E M E T F V S C-term D A I P I L Y Y I I F V I G F L V N I V V V T L F C C Q V S S I Y I F N L A V A D L L L L A T L P L W A T Y Y S Y R G P V M C K V F G S F L T L N M F A S I F F I T C M S V D R Y Q S V I Y N P W Q A S Y I V P L V W C M A C L S S L P T F Y F R K Y A Q W S A G I A L M K N I L G F I I P L I F I A T C Y F G I R K H L L K T G K N R I T R D Q V L K M A A A V V L A F I I C W L P F H V L T F L D A L A W M G S C E V I A V I D L A L P F A I L L G F T N S C V N P F L Y C F V G N R L R S P F Q Q K V F R V
Helix box plot — Download: PNG | SVG I N V L F G I V F I I Y Y L I P I A D 1 F N L A V A D L L L L A T L P L W A T Y 2 C T I F F I S A F M N L T L F S G F V K 3 A S Y I V P L V W C M A C L S S L P T 4 Y C T A I F I L P I I F G L I N K M L A I 5 A A V V L A F I I C W L P F H V L T F L 6 F P N V C S N T F G L L I A F P L A L 7

GPCRdb(A)
GPCRdb(A)
AT2 receptor
TM2
2x60 2.60x60 W100
2x63 2.63x63 Y103
2x64 2.64x64 Y104
TM3
3x32 3.32x32 L124
3x33 3.33x33 T125
3x36 3.36x36 M128
TM4
4x65 4.64x65 R182
ECL2
45x50 45.50x50 C195
45x51 45.51x51 I196
45x52 45.52x52 M197
TM5
5x32 5.31x32 Y204
5x43 5.42x43 K215
TM6
6x48 6.48x48 W269
6x51 6.51x51 F272
6x58 6.58x58 D279
6x62 6.62x62 W283
TM7
7x27 7.28x27 I293
7x31 7.32x31 D297
7x34 7.35x34 L300
7x35 7.36x35 P301
7x38 7.39x38 I304