angiotensin II (Human) [866]



angiotensin II (Human)


SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O
InChIKey CZGUSIXMZVURDU-JZXHSEFVSA-N
Sequence DRVYIHPF
HELM PEPTIDE1{D.R.V.Y.I.H.P.F}$$$$

Chemical Properties

Hydrogen bond acceptors 13
Hydrogen bond donors 13
Rotatable bonds 29
Log P -1.315
Molecular weight (Da) 1045.5
Stereochemistry info partial

Database connections

Structure pdb 6JOD 6OS0
Model (AF2) AT1 AT2
Model (Boltz2) AT1
GPCRdb related ligands

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

angiotensin II (Human)


Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug Yes

Distribution across phases (no. indications)

Phase I 2
Phase II 0
Phase III 0
Phase IV 2

Database connections

Structure pdb 6JOD 6OS0
Model (AF2) AT1 AT2
Model (Boltz2) AT1

Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score