Structure information

TAAR7F

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8PM2

SPECIES

Mus musculus

RESOLUTION

2.920

PREFERRED CHAIN

R

REFERENCE

10.1101/2023.07.07.547762

PUBLICATION DATE

Aug. 9, 2023

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
N,N-Dimethylcyclohexylamine D127 3.32x32 TM3 polar (charge-assisted hydrogen bond)
N,N-Dimethylcyclohexylamine C131 3.36x36 TM3 Van der Waals
N,N-Dimethylcyclohexylamine Y132 3.37x37 TM3 hydrophobic
N,N-Dimethylcyclohexylamine Y132 3.37x37 TM3 Van der Waals
N,N-Dimethylcyclohexylamine N217 5.43x44 TM5 Van der Waals
N,N-Dimethylcyclohexylamine W286 6.48x48 TM6 hydrophobic
N,N-Dimethylcyclohexylamine W286 6.48x48 TM6 Van der Waals
N,N-Dimethylcyclohexylamine Y289 6.51x51 TM6 Van der Waals
N,N-Dimethylcyclohexylamine Y289 6.51x51 TM6 hydrophobic
N,N-Dimethylcyclohexylamine V312 7.39x38 TM7 hydrophobic
N,N-Dimethylcyclohexylamine V312 7.39x38 TM7 Van der Waals
N,N-Dimethylcyclohexylamine V315 7.42x41 TM7 hydrophobic
N,N-Dimethylcyclohexylamine V315 7.42x41 TM7 Van der Waals
N,N-Dimethylcyclohexylamine Y316 7.43x42 TM7 hydrophobic
N,N-Dimethylcyclohexylamine Y316 7.43x42 TM7 Van der Waals

Ligands

N,N-Dimethylcyclohexylamine

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Residue Diagrams

L N G C V A L V A G F G F V A Y L I L R 1 A S L A C A D F L V G M V V M P F S M V R 2 F C L H F L S C Y C F S V D F C T H L K 3 S G K C I T F S W L L S I S Y G F S L I 4 Y V T I M V L T P I L F V S F N I F V W T 5 G I A V A A F L L S W L P Y F I D S F I 6 L P N M A S N Y Y V I W V L I E Y V Y 7
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ICL1 R Q L H ICL1ECL1 C W Y F ECL1ICL2 P L A Y P T R F ICL2ECL2 A S E A G L E D L V S S L T C V G G C Q I A V ECL2ICL3 R A S D S Y ICL3ECL3 G F I T ECL3N-term M S I A D E T V S W N Q D S I L S R D L F S A T S A E L C Y E N L N R S C V R N-termC-term G K I L R E N S S T T N L F S E C-term S P Y S P G P R L I L Y A V F G F G A V L A V C G N L L V M T S I L H F S P A N F L V A S L A C A D F L V G V M V M P F S M V R S V E G G D S Y C K L H T C F D V S F C Y C S L F H L C F I S V D R Y I A V S D T A S V S G K C I T F S W L L S I S Y G F S L I Y T G N Q T W V F I N F S V F L I P T L V M I T V Y S K I F L I A K Q Q A Q N I E K M S K Q T A K D R V A K R E R K A A K T L G I A V A A F L L S W L P Y F I D S F I D A F L P T Y V Y E I L V W I V Y Y N S A M N P L I Y A F F Y P W I K L F R K A T V T
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Residue Table


GPCRdb(A)
GPCRdb(A)
TAAR7F
TM3
3x32 3.32x32 D127
3x36 3.36x36 C131
3x37 3.37x37 Y132
TM5
5x44 5.43x44 N217
TM6
6x48 6.48x48 W286
6x51 6.51x51 Y289
TM7
7x38 7.39x38 V312
7x41 7.42x41 V315
7x42 7.43x42 Y316