cagrilintide [1610]



cagrilintide

No image available
SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](CCCCN)NC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCCCC(=O)O)C(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)[C@@H](C)O)C(=O)N[C@H](CC(C)C)C(=O)N1CCC[C@@H]1C(=O)N1CCC[C@@H]1C(=O)N[C@@H](C(=O)N[C@H](CC(N)=O)C(=O)N[C@@H](C(=O)NCC(=O)N[C@H](CO)C(=O)N[C@H](CC(N)=O)C(=O)N[C@@H](C(=O)N1CCC[C@@H]1C(N)=O)[C@H](C)O)C(C)C)[C@H](C)O
InChIKey LDERDVMBIYGIOI-IZVMHKDJSA-N
Sequence None

Chemical Properties

Hydrogen bond acceptors 62
Hydrogen bond donors 60
Rotatable bonds 135
Log P -19.057
Molecular weight (Da) 4406.3
Stereochemistry info partial

Database connections

Structure pdb 9BUB 9UWM 9UWQ 9BP3 9BQ3 9BTW 9BUC 9BUD 9BUE

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

cagrilintide

No image available

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug Yes

Distribution across phases (no. indications)

Phase I 0
Phase II 0
Phase III 0
Phase IV 0

Database connections

Structure pdb 9BUB 9UWM 9UWQ 9BP3 9BQ3 9BTW 9BUC 9BUD 9BUE

Compound is not listed as a drug.