L-367,773


SMILES O=C(Cc1cnc[nH]1)N[C@H]1C[C@@H]2C([C@]1(CC2)CS(=O)(=O)N1CCC2(CC1)CCc1c2cccc1)(C)C
InChIKey VQAVBHLGXVZOKM-RASJMTDNSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 510.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OT OXYR Human Vasopressin and oxytocin A pKi 7.6 7.6 7.6 Guide to Pharmacology
OT OXYR Human Vasopressin and oxytocin A pKi 7.21 7.21 7.21 ChEMBL
OT OXYR Rat Vasopressin and oxytocin A pKi 7.58 7.58 7.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
V2 V2R Rat Vasopressin and oxytocin A pIC50 4.77 4.77 4.77 ChEMBL
OT OXYR Rat Vasopressin and oxytocin A pIC50 7.28 7.28 7.28 ChEMBL